摘要
目的对左乙拉西坦(开浦兰)加用和单用治疗癫痫的疗效及不良反应进行观察研究。方法241例癫痫患者,125例加用开浦兰治疗,116例单用开浦兰治疗。结果共有225例患者完成了20周疗程的观察。开浦兰加用治疗总有效率达60.17%,单用治疗达73.83%。结论开浦兰加用及单用治疗癫痫均有较好疗效,是一种广谱、安全、耐受性好的新型抗癫痫药物。
Objective To observe and evaluate the the clinical effect and the side effect of Levetiracetam（Lev） both in add-on therapy and mono-therapy.Methods Total 241 epileptic patients were observed,125 of them were given Lev by add-on therapy while 116 cases by Lev mono-therapy.Results 225 cases completed a course of 20 weeks＇therapy.In add-on therapy group,the effective rate of Lev achieved 60.17% in mono-therapy group,it reached 73.83%.It showed that both mono and add-on therapy of Lev were effective to all of the seizure types.Conclusion Lev had satisfactory therapeutic effect both in mono and add-on therapy.It is a new broad spectrum,safe and well tolerated antiepileptic drug.
出处
《医药论坛杂志》
2010年第6期23-24,27,共3页
Journal of Medical Forum
