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TCD对颅脑外伤后脑血管痉挛的研究 被引量:8

Using Transcranial Doppler to Study the Cerebral Vasospasm after Craniocerebral Injury
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摘要 目的:探讨TCD监测颅脑外伤后脑血管痉挛的血流动力学变化规律及与伤情的关系。方法:选择80例于伤后24小时内入院的颅脑外伤患者,于入院第1、2、3、4、5、6、7、14天行TCD检测患者大脑中动脉平均血流速度(VmMCA)。健康成人大脑中动脉平均血流速度作为对照比较,并对合并蛛网膜下腔出血组和未合并蛛网膜下腔出血组进行比较,对轻、中、重度患者进行分组比较。结果:患者伤后1~3天出现大脑中动脉流速增快,4~6天达高峰,14天已明显减轻;合并蛛网膜下腔出血的患者脑血管痉挛的发生率高于不合并蛛网膜下腔出血的患者(P<0.05);病情越重,脑血管痉挛程度越重。结论:TCD可以及时、准确、无创的对颅脑外伤后脑血管痉挛进行监测,有利于早期发现血管痉挛的发生及严重程度,可以作为指导治疗的一个指标。 Objective To explore the role of transcranial Doppler (TCD) to observe the hemodynamic of cerebral vasospasm after craniocerebral injury and the relationship with traumatic severity.Methods The blood flow velocity of middle cerebral artery (VmMCA) was measured by TCD on the 1st,2nd,3rd,4th,5th,6th,7th and 14th day in 80 cases with craniocerebral injury patients who were hospitalized within 24 hours.Then the VmMCA of craniocerebral injury cases was compared with the VmMCA of 40 healthy adults,and comparison was made between the groups of subarachnoid hemorrhage (SAH) and non-SAH,and among the groups of slight、moderate and severe craniocerebral injury.Results The blood flow velocity in the middle cerebral artery (MCA) during 1-3 days after injury was getting faster and reached its peak at 4-6 days,then gradually fell back down in 14 days.The incidence rate in cerebral vasospasm of the SAH group was significantly higher than that in non-SAH(P0.05).The severity of cerebral vasospasm is proportional to the patients' conditions.Conclusions TCD can be a timely,accurate and non-invasive way to detect cerebral vasospasm following craniocerebral injury,and is also conducive to early detection of vasospasm and severity,can be used as an indicator to guiding treatment.
出处 《心脑血管病防治》 2010年第2期90-92,共3页 CARDIO-CEREBROVASCULAR DISEASE PREVENTION AND TREATMENT
关键词 TCD 颅脑外伤 脑血管痉挛 TCD Craniocerebral injury Cerebral vasospasm
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  • 1X.H. LIU~(1,2) H. HUANG~1 C. YU~1 M.J. ZOU~1 X. WANG~3 1(Institute of Biomedical Engineering, Center of West China Medical Sciences, Sichuan University, Chengdu 610041, China)2(Laboratory of Cardiovascular Diseases, West China Hospital, Sichuan University, Chengdu 610041, China)3(LEMTA-UMR-CNRS 7563, Vandoeuvre-les-Nancy, 54500, BP160, France).Cell-fluid Interaction: Coupling Between the Deformation of an Adherent Leukocyte and the Shear Flow[J].生物医学工程学杂志,2005,22(S1). 被引量:2
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