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血友病A患者产生凝血因子Ⅷ抑制物的治疗相关危险因素 被引量：1

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摘要 血友病A的治疗以凝血因子替代治疗为主。替代治疗目前存在的主要问题为血友病患者输注FⅧ制剂后产生针对FⅧ的中和性抗体，其发生率国外各家报道差异较大，危险因素包括患者相关因素（疾病严重程度、患者的种族、基因型和免疫反应）和治疗相关因素（替代治疗的起始时间、种类、剂量和方式），本综述主要阐述了国内外治疗相关危险因素的研究现状。
作者 王志伟(综述) 赵永强(审校)
机构地区 北京协和医学院中国医学科学院北京协和医院血液科
出处 《国际输血及血液学杂志》 CAS 2010年第2期137-139,共3页 International Journal of Blood Transfusion and Hematology
基金 基金项目：北京市首都医学发展科研基金（20051024）
关键词 血友病A 凝血因子Ⅷ抑制物 治疗相关危险因素
分类号 R554.1 [医药卫生—血液循环系统疾病]
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参考文献29

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二级参考文献18

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国际输血及血液学杂志
2010年 第2期

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