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甲状腺自身抗体的基础和临床进展 被引量：32

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摘要 迄今已知的人类甲状腺自身抗原有促甲状腺激素受体（TSHR）、甲状腺球蛋白（TG）、甲状腺过氧化物酶（TPO）和钠-碘转运体（NIS）4种,与其相对应的抗体分别为TSHR抗体（TRAbs）、TGAb、TPOAb和anti—NIS。
作者 刘超 杨昱 陈立立
机构地区 南京医科大学第一附属医院内分泌科 苏州大学附属第二医院内分泌科
出处 《内科理论与实践》 2010年第2期139-146,共8页 Journal of Internal Medicine Concepts & Practice
关键词 甲状腺过氧化酶抗体 促甲状腺激素受体抗体 自身免疫性甲状腺疾病 GRAVES病 桥本甲状腺炎
分类号 R581 [医药卫生—内分泌]
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参考文献51

  • 1MeLachlan SM,Rapoport B.Thyroid peroxidase as an autoantigen[J].Thyroid,2007,17(10):939-948.
  • 2Hofman LF,Foley TP,Henry J J,et al.The use of filter paper-dried blood spots for thyroid-antibody screening inadults[J].J Lab Clin Med,2004,144(6):307-312.
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二级参考文献16

  • 1Pop VJ, Brouwers EP, Vader HL, et al. Maternal hypothyroxinaemia during early pregnancy and subsequent child development: a 3-year follow-up study. Clin Endocrinol ( Oxf), 2003,59:282-288.
  • 2Haddow JE, Palomaki GE, Allan WC, et al. Maternal thyroid deficiency during pregnancy and subsequent psychological development in the child. N Engl J Med, 1999,341:549-555.
  • 3Pop VJ, Kuijpens JL, van Baar AL, et al. Low maternal free thyroxine concentrations during early pregnancy are associated with impaired psychomotor development in infancy. Clin Endocrinol (Oxf), 1999, 50 : 149-155.
  • 4Abalovich M, Amino N, Barbour LA, et al. Management of thyroid dysfunction during pregnancy and postpartum: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab, 2007,92:S1- S47.
  • 5李玉姝 单忠艳 滕卫平 等.甲状腺自身抗体TPOAb和TGAb正常值的研究意义[J].中华检验杂志,2006,29:780-783.
  • 6Cuevas E, Auso E, Telefont M, et al. Transient maternal hypothyroxinemia at onset of cortieogenesis alters tangential migration of medial ganglionic eminence-derived neurons. Eur J Neurosci, 2005, 22:541-551.
  • 7Gilbert ME, Sui L, Walker MJ, et al. Thyroid hormone insufficiency during brain development reduces parvalbumin immunoreactivity and inhibitory function in the hippocampus. Endocrinology, 2007,148:92- 102.
  • 8Lavado-Autric R, Auso E, Garcia-Velasco JV, et al. Early maternal hypothyroxinemia alters histogenesis and cerebral cortex cytoarchitecture of the progeny. J Clin Invest, 2003,111:1073-1082.
  • 9Auso E, Lavado-Autric R, Cuevas E, et al. A moderate and transient deficiency of maternal thyroid function at the beginning of fetal neocorticogenesis alters neuronal migration. Endocrinology, 2004,145 : 4037-4047.
  • 10Rosa MC, Eric J, Beatrice G, et al. Fetal tissues are exposed to biologically relevant free thyroxine concentrations during early phases of development . J Clin Endocrinol Metab, 2002,87:1768-1777.

共引文献72

同被引文献282

引证文献32

二级引证文献268

内科理论与实践
2010年 第2期

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