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U形管引流在晚期肝门部胆管癌治疗中的应用

U-fashion Tube Drainage in Advanced Hilar Cholangiocarcinoma.
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摘要 目的:评价U形管引流对晚期肝门胆管癌的治疗效果。方法:对17例无法手术切除的晚期肝门胆管癌行U形管置入引流术。结果:17例患者术后总胆红素逐渐下降,术后第7d总胆红素为(113.4±51.1)mmol/L,较术前存在显著性差异(P<0.05)。白蛋白水平升高明显,ALT、AST、r-GT显著降低。术后随访率76.4%,平均生存期为11.6个月。结论:U形管引流术适用于不能根治切除或姑息性切除的晚期肝门胆管癌,可有效解除黄疸,改善肝功能,提高病人生存质量及延长生存期。 Objective To evaluate the effect of U-fashion tube drainage in inoperable advanced hilar cholangiocarcinoma.Methods The hospital charts of all patients with inoperable hilar cholangiocarcinoma who had U-fashion tubes placed between 2003 and 2007 were reviewed retrospectively.Results Serum level of total bilirubin dropped gradually after surgery.It decreased to 113.4±51.1 mmol/L seven days post-surgery and was significantly different from that before surgery(P 〈0.05).Concentration of serum albumin increased significantly and levels of alanine aminotransferase(ALT),aspartate aminotransferase(AST) and γ-glutamyltransferase(GGT) decreased notably.The rate of follow-up was 76.4% and the mean survival period was 11.6 months.Conclusion U-fashion tube drainage could be applied to inoperable advanced hilar cholagiocarcinoma to improve quality of life and prolong survival,since it relieves biliary obstruction and improves hepatic function.
出处 《中国中西医结合外科杂志》 CAS 2010年第2期154-156,共3页 Chinese Journal of Surgery of Integrated Traditional and Western Medicine
关键词 U形管引流 肝门部 胆管癌 U-fashion tube drainage advanced hilar cholangiocarcinoma
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