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186例鼻咽癌疗效分析

Clinical Analysis of 186 Patients with Nasopharyngeal Carcinoma
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摘要 对鼻咽癌常规外照射疗效进行分析,探讨方法的改进,以期提高疗效。方法:186例经病理证实鼻咽癌病人,接受常规60Co根治性分段外照射,鼻咽和颈部DT60~72Gy/9~11周,中间休息3~4周。分析其5年生存率及死亡原因。结果:按照TNM(长沙,1979)分期5年生存率分别为:Ⅰ期100%(1/1);Ⅱ期533%(27/45);Ⅲ期464%(45/97);Ⅳ期20%(9/43);总的5年生存率为441%(82/186)。结论:对Ⅰ~Ⅱ期病人以设法提高局部控制率为主;对Ⅲ~Ⅳ期病人在提高局部控制率同时,必须综合全身化疗。 Objective:To analyze the effect of conventional radiotherapy for patients with nasopharyngeal carcinoma,and to give suggestions about how to improve the prognosis of the nasopharyngeal carcinoma. Methods:186 patients with pathologically confirmed nasopharyngeal carcinoma underwent a conventional 60 CoA external radiation.The nasopharynx and cervix received a dose 60~70 Gy/9~11weeks, and had a interval of 3~4 weeks after 40 Gy.The 5 years survival rate and cause of death were analyzed. Results: According to TNM classification (Changsha 1979),the 5 years survival rate in Ⅰ,Ⅱ,Ⅲand Ⅳstage was 100%(1/1),53 3%(27/45),46 4%(45/97) and 20 9%(9/43), respectively. The overall 5 years survival rate was 44 1%(82/186). Conclusion: The main task is to prevent the local recurrence for Ⅰ~Ⅱ stage of nasopharyngeal carcinoma , and a combined chemotherapy should be added in order to prevent the distant metastases for Ⅲ~Ⅳ stage.
出处 《暨南大学学报(自然科学与医学版)》 CAS CSCD 1998年第6期73-73,共1页 Journal of Jinan University(Natural Science & Medicine Edition)
关键词 鼻咽癌 放射治疗 疗效分析 nasopharyngeal carcinoma radiotherapy analysis
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