摘要
多糖是生物体内普遍存在的一类生物大分子，具有广泛的生理功能，对免疫系统，促进抗体的产生，促进多种细胞因子的生成，促进干扰素、白细胞介素等的生成；激活巨噬细胞、自然杀伤（NK）细胞和T、B淋巴细胞，激活补体系统；多糖通过与淋巴细胞表面CR3受体结合而发挥作用，影响细胞内[Ca^2＋]i、cAMP、cGMP、NO和PGE2等第二信使的决定，并可促进细胞因子基因的表达，多糖的活性与单核组成、相对分子质量、高级结构、糖苷键类型等有关.
Polysaccharides is a kind of widespread biological macromolecules in organism. It has many functions such as actiavting the lymphocytes like anti -bodies, promoting the secretion of many cytokines and T, B, NK cells through binding to the CR3 receptor of lymphocytes, affecting the concentrations of cellar, [ Ca^2＋ ] i , cAMP, cCMP, NO and PGE2, and promoting the gene expression of cytokines. Its function also relate to its molecule weight and structure.
出处
《中国饲料添加剂》
2008年第3期10-14,共5页
China Feed Additive
关键词
多糖
免疫调节
基因表达
第二信使
受体
polysaccharide
immunoregulation
gene expression
signal transduction
receptor
