摘要
目的:应用小剂量奎硫平治疗顽固性失眠做以研究阐述。方法:符合入组标准42人,治疗前均应用匹兹堡睡眠质量指数(PSQI)量表评分,分别给予小剂量奎硫平晚1次口服,分别于2、4、6、8、12周后再次应用PSQI量表评分。结果:3人失访,2人因不能耐受停药,37人病情明显好转,3人治愈,12周PSQI量表减分率17.23±2.77(P<0.01)。结论:小剂量奎硫平治疗顽固性失眠疗效肯定,耐受性好,值得推广。
Objective：of low- dose quetiapine in the treatment of refractory insomnia done to study and expound. Methods： 42 people in line into the group of standards, pre - treatment were applied Pittsburgh Sleep Quality Index （PSQI） Scale score （ 1 ） , were given low - close oral administration of quetiapine once a night, respectively, 2 weeks 4 weeks 6 weeks 8 weeks 12 weeks after the re- application of PSQI Scale. Results： The three people were lost, two people because they can not tolerate withdrawal, 37 were markedly improved condition, 3 were cured, 12 weeks PSQI sub- scale scores lowered rate minus the rate of 17.23 ＋ 2.77 （P 〈 0. 01 ）. Conclusions： Low- dose quetiapine in the treatment of refractory insomnia efficacy sure, well tolerated, it is worth promoting.
出处
《中国民康医学》
2010年第9期1144-1144,1188,共2页
Medical Journal of Chinese People’s Health
关键词
小剂量奎硫平
顽固性失眠
Of low - dose quetiapine
Refractory insomnia
