期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

大鼠嗜碱性粒细胞在过敏反应研究中的应用 被引量：2

The application of RBL cell in allergy study
下载PDF
导出
摘要 中药注射剂目前在临床上应用广泛,但诸多不良反应限制了其应用和发展。过敏反应是中药注射剂的主要不良反应,直接关系到中药注射剂安全性问题的解决。本研究综述了RBL细胞在过敏反应中的应用进展,期望能为中药注射剂的过敏反应的研究提供一些思路。 The Traditional Chinese Medicine Injection （TCMI） is widely used in the clinic;however the occurrence of ad- verse reactions restricted its use and development. The allergy,which is the main cause of TCMI adverse reactions, is related to the solution of the safety problems caused by TCMI, In this review we summarized the process of application of RBL cell in al- lergy, providing some research ideas for the study of allergy caused by TCMI.
作者 刘宝峰 李中港 刘兆平
机构地区 山东大学药学院
出处 《齐鲁药事》 2010年第4期230-232,共3页 qilu pharmaceutical affairs
关键词 中药注射剂 过敏反应 大鼠嗜碱性粒细胞 TCMI Allergy RBL cell
分类号 R994.1 [医药卫生—毒理学]
  • 相关文献

参考文献22

  • 1张曙光,候涛,阎仁智.脉络宁注射液致过敏性休克1例[J].齐鲁药事,2009,28(6):380-380. 被引量：8
  • 2黄帅.热毒宁注射液致过敏性休克1例[J].齐鲁药事,2009,28(9):573-573. 被引量：24
  • 3程芳,刘兆平.中药注射剂安全性评价与关键技术的研究[J].中国中药杂志,2009,34(8):1052-1054. 被引量：47
  • 4张嘉,李澎,李贻奎,李连达.吐温80诱导RBL-2H3细胞脱颗粒作用研究[J].现代免疫学,2009,29(3):240-245. 被引量：37
  • 5Passante E,Frankish N.The RBL-2H3 cell line:its provenance and suitability as a model for the mast cell.Inflamm Res,2009,58(11):737-745.
  • 6Porterfield HS,Murray KS,Schlichting DG,et al.Effector activity of peanut allergens:a critical role for Ara h2,Ara h6,and their variants.Clin Exp Allergy,2009,39(7):1099-1108.
  • 7Kaul S,Scheurer S,Danz N,et al.Monoclonal IgE antibodies against birch pollen allergens:novel tools for biological characterization and standardization of allergens.J Allergy Clin Immunol,2003,111(6):1262-1268.
  • 8King N,Helm R,Stanley JS,et al.Allergenic characteristics of a modified peanut allergen.Mol Nutr Food Res,2005,49(10):963-971.
  • 9Kaul S,Lüttkopf D,Kastner B,et al.Mediator release assays based on human or murine immunoglobulin E in allergen standardization.Clin Exp Allergy,2007,37(1):141-50.
  • 10Dibbern DA,Palmer GW,Williams PB,et al.RBL cells expressing human Fc epsilon RI are a sensitive tool for exploring functional IgE-allergen interactions:studies with sera from peanut-sensitive patients.J Immunol Methods,2003,274(1-2):37-45.

二级参考文献88

共引文献156

同被引文献31

  • 1曹学东.9种中药注射剂不溶性微粒观察.中医药研究,2004,11(5):55-55.
  • 2Szebeni J,Alving C R,Rosivall L,et al.Animal models of com plement-mediated hypersensitivity reactions to liposomes and other lipid-based nanoparticles[J].Liposome Res,2007,17(2):107-117.
  • 3Chai X,Li S and Li P.Quality evaluation of Flos Lomcerae through a simultaneous determination of seven saponins by HPLC with ELSD[J].J of Chromatogr A,2005,1070(1-2):43-48.
  • 4Gauthier C,Legault J,Girard-Lalancette IC,et al.Haemolytic ac tivity,cytotoxicity and membrane cell permeabilization of semi synthetic and natural lupane-and oleanane-type saponins[J].Bioorg med chem,2009,17(5):2002-2008.
  • 5Ren M,Chen J,Song Y,Sheng Let alddentification and quantifi cation of 32 bioactive compounds in Lonicera species by high performance liquid chromatography coupled with time-of-flight mass spectrometry[J].J pharm biomed anal,2008,48(5):1351-1360.
  • 6Lvir M,Alberg T,Nygaard U,et al.Popliteal lymph node (PLN)assay to study adjuvant effects on respiratory allergy[J].Methods,2007,41:72-79.
  • 7Ravel G and Descotes J.Popliteal lymph node assay:facts and per spectives[J] J Appl Toxico1,2005,25(6):451-458.
  • 8Li Z,Gao Y,Wang H,et al.A rat model of Shuang Huang Liam injection-induced anaphylaxis[J].Asian Pac J Allergy Immunol,2010,28(2-3):185-191.
  • 9FDA:Guidance for Industry Inununotoxicology Evaluation of In vestigational New Drugs[EB/OL].20M.http://www.fda.gov/downlo ads/Drugs/GuidanceComplianceRegulatorylnfonnation/Guidan ces/ucm079239.pdf.
  • 10Choi YH,Yan GH.Silibinin attenuates mast cell-mediated ana phylaxis like reactions[J].Biol Pharm Bull,2009,32(5):868-875.

引证文献2

二级引证文献16

齐鲁药事
2010年 第4期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部