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阿尔茨海默病的生物学标志及其靶向治疗 被引量:8

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摘要 阿尔茨海默病(AD)是临床最为常见的老年期神经变性疾病之一,其病理学特征表现为神经炎性斑[NPs,又称老年斑(SPs)]和神经原纤维缠结(NFTs)形成,基底节区和前脑胆碱能神经元大量缺失;临床主要表现为进行性认知损害和记忆力减退,致生活不能自理,直至死亡。
作者 王政 乐卫东
出处 《中国现代神经疾病杂志》 CAS 2010年第2期151-154,共4页 Chinese Journal of Contemporary Neurology and Neurosurgery
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