摘要
目的回顾性分析北京地坛医院收治的257例艾滋病(AIDS)病人机会性感染的总体情况,进一步了解机会性感染的致病谱。方法对该院2006年以来收治的257例AIDS病人,就机会性感染的总体情况,分别从流行病学、临床症状和体征、实验室及影像学检查结果、免疫水平进行综合分析。结果呼吸系统机会性感染发生比例为65.25%,主要表现为肺部感染(细菌性、病毒性、真菌性),肺结核、卡氏肺孢子虫肺炎(PCP)等;消化系统机会性感染的发生比例为40.47%,主要为口腔真菌感染、巨细胞病毒(CMV)肠炎、霉菌性食道炎等;神经系统机会性感染的发生比例为9.34%,主要为隐球菌脑膜炎、进行性多病灶脑白质病、细菌性中枢神经系统感染等;其他部位机会性感染的发生比例为30.35%,主要为CMV视网膜炎、淋巴结结核、带状疱疹等。结论呼吸系统和消化系统是AIDS病人发生机会性感染的常见部位,其次是神经系统和全身性。而细菌性肺部感染、结核病、CMV感染、PCP、真菌感染,是AIDS病人主要就诊和住院的机会性感染。
Objective To retrospectively analyze the overall characteristics of opportunistic infection in 257 AIDS patients in Beijing Ditan Hospital so as to understand the pathogenic spectrum of their opportunistic infections . Methods A total of 257 AIDS inpatients admitted to Beijing Ditan Hospital since 2006 were enrolled. Clinical, epidemic, laboratory and immunological characteristics were retrospectively analyzed. Results Opportunistic infection of the respiratory system accounted for 65.25% , including pulmonary infection （bacteria, fungi, virus ）, pulmonary tuberculosis ,PCP; opportunistic infection of the digestive system accounted for 40.47% , including oral candidiasis , CMV enteritis, fungal esophagitis; opportunistic infection of the nervous system accounted for 9.47%,including cryptococcus meningitis, PML, bacterial infection of the central nervous system; opportunistic infection of other systems accounted for 30.35%, including CMV retinitis, lymphonode tuberculosis, herpes zoster. Conclusion The common system effected with opportunistic infection in AIDS patients is the respiratory and digestive system, followed by the nervous system and systemic infections. The main opportunistic infections among AIDS outpatients and inpatients are bacteria pulmonary infection, tuberculosis, CMV infection, PCP, and fungal infection
出处
《中国艾滋病性病》
CAS
2010年第2期134-137,共4页
Chinese Journal of Aids & STD
基金
北京市科技计划研发攻关基金赞助(编号:D0906003040291)~~
关键词
艾滋病病人
总体情况
机会性感染
Human immunodeficiency virus
Acquired immunodeficiency syndrome
Overall characteristics
Opportunistic infection
