摘要
目的:探讨孟鲁司特加布地奈德治疗儿童中度哮喘的临床效果。方法:将2008年1月至2009年12月间在我院住院治疗的中度哮喘患儿60例随机分为A组、B组和C组,A组单纯应用布地奈德,B组单纯应用孟鲁司特,C组联合应用布地奈德和孟鲁司特气雾剂,评估三组治疗效果。结果:治疗后三组患儿哮喘症状评分、肺功能均较治疗前好转,三组分别比较差异具有统计学意义(P<0.05)。C组哮喘症状评分和肺功能明显优于A组、B组,两组分别比较差异具有统计学意义(P<0.05)。A组总有效率为70.00%,B组为75.00%,C组为95.00%;A组、B组总有效率明显低于C组,两组分别比较差异具有统计学意义(P<0.05);A组总有效率与B组比较差异无统计学意义(P>0.05)。治疗过程中三组均未见明显的治疗副作用。结论:孟鲁司特联合布地奈德治疗儿童中度哮喘疗效优于两者单纯用药,值得推广应用。
Objective：To investigate the effect of montelukast combined with budesonide on treatment of children with midrange asthma.Method：60 cases with midrange asthma in our hospital from Jan.in 2008 to Dec.in 2009 were divided into A group,B group and C group,A group received the treatment of budesonide,the B group received the treatment of montelukast,and the C group received the treatment of montelukast combined with budesonide aerosol.Results：The score of symptoms of asthma and lung function in three groups after treatment was superior to that before treatment,and there was significant difference in them respectively（P〈0.05）.The score of symptoms of asthma and lung function in C group was superior to that in A group and in B group,and there was significant difference in them respectively（P〈0.05）.The total effective rate was 70.00% in A group,75.00% in B group and 95.00% in C group,and the total effective rate in A group and in B group was lower than that in C group,and there was significant difference in them respectively（P〈0.05）.The total effective rate in B group was the same to that in A group,and there was no significant difference in them respectively（P〉0.05）.Conclusion：The effect of montelukast combined with budesonide on treatment of children with midrange asthma is superior to one of the two drugs,they are worth being used widly.
出处
《河北医学》
CAS
2010年第4期400-402,共3页
Hebei Medicine
