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老年非小细胞肺癌XIAP蛋白的表达及临床意义 被引量：5

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摘要 目的观察XIAP蛋白在老年非小细胞肺癌(NSCLC)中的表达。方法应用蛋白质印迹法检测39例NSCLC肿瘤组织和癌旁组织中XIAP蛋白的表达情况及其临床意义。结果NSCLC肿瘤组织XIAP蛋白阳性率为62%,阳性病例中XIAP蛋白的相对表达量高于癌旁组织(P<0.01)。高表达的XIAP蛋白与患者的性别、年龄、吸烟史、淋巴结转移无关,与肿瘤临床分期、病理分级有关(P<0.05)。结论XIAP蛋白可能是判断老年NSCLC预后的重要指标之一。
作者 王丽波 华树成 刘伟
机构地区 吉林大学第一医院胃肠内科 吉林大学第一医院呼吸内科 吉林大学第一医院胸外科
出处 《中国老年学杂志》 CAS CSCD 北大核心 2010年第8期1059-1060,共2页 Chinese Journal of Gerontology
关键词 非小细胞肺癌 XIAP 蛋白质印迹
分类号 R734.2 [医药卫生—肿瘤]
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参考文献9

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二级参考文献10

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中国老年学杂志
2010年 第8期

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