摘要
目的:对白背三七地上部分进行化学成分研究。方法:应用硅胶柱、薄层制备、葡聚糖凝胶等色谱技术分离纯化,应用波谱技术确定化合物的结构。结果:从白背三七中分离得到了10个化合物,分别为:2-(1,′2,′3,′4′-四羟基丁基)-6-(2,″3,″4″-三羟基丁基)-吡嗪(1)、掌叶半夏碱庚(2)、烟酸(3)、5-羟基吡啶羧酸(4)、5-羟基吡啶-2-甲酸甲酯(5)、腺苷(6)、尿苷(7)、豆甾醇葡萄糖苷(8)、对苯二甲酸二丁酯(9)、绿原酸甲酯(10)。结论:化合物1、2、5、9、10为首次从该属植物中分离得到,化合物3、4为首次从该植物中分离得到。
Objective:To study the chemical constituents from aerial parts of Gynura divaricata.Methods:The constituents were isolated on silica gel column chromatography,preparative TLC and Sephadex LH-20 column chromatography,identified by physicochemical properties and the sturctures were elucidated by spectral analysis.Results:10 compounds were isolated and identified as 2-(1′,2′,3′,4′-tetrahydroxybutyl)-6-(2″,3″,4″-trihydroxybutyl)-pyrazine(1),2-(1′,2′,3′,4′-tetrahydroxybutyl)-5-(2″,3″,4″-trihydroxybutyl)-pyrazine(2),nicotinic acid(3),5-hydroxy-picolinic acid(4),methyl-5-hydroxy-2-pyridinecarboxylate(5),adenosine(6),uridine(7),stigmasterol-5-O-β-D-glucoside(8),dibutyl terephthalate(9),methyl chlorogenate(10).Conclusion:Compounds 1,2,5,9,10 are obtained from this genus for the first time,Compounds 3,4 are obtained from this plant for the first time.
出处
《中药材》
CAS
CSCD
北大核心
2010年第3期373-376,共4页
Journal of Chinese Medicinal Materials
基金
福建省科技计划重点项目(2008Y0086)
福建省卫生厅中医药科研项目(wzy0606)
关键词
白背三七
地上部分
化学成分
Gynura divaricata(L.)DC.
Aerial parts
Chemical constituents