摘要
目的改进本实验室与重庆大学联合研制的高敏度小张力膜状生物材料力学检测装置并测试其准确度及稳定性。方法①将原仪器液-气压力加载系统改为气体加载系统;②将夹具升级为可轴向运动,夹持稳固、精确,可视的夹持系统;③更换为高精度、量程为20kPa的传感器,并对系统软件内参数作相应调整;④对仪器准确度、稳定性进行测试。结果①成功地将原仪器改进成外形小巧,夹持可靠,试件变化可视,操作方便、快捷的装置。②准确度测试结果:引用误差为-0.30%～+0.29%之间。③稳定性测试:不同日期5个不同时段测得同一标准品的数据[分别为(18723±16)、(18705±5)、(18720±23)、(18731±15)、(18733±20)Pa]之间差异无统计学意义(P>0.05)。结论经改进后仪器能准确测量出组织工程皮肤等膜状生物材料的抗张强度。
Objective To improve the high-sensitivity mechanical test device for detecting the properties of small tension membranaceous biomaterials produced in our laboratory and Chongqing University and examine its accuracy and stability.Methods The original air-liquid pressure loading system was replaced by an airy pressure loading system.The clamp was upgraded to a visual clamping system which can be moved along the axial direction and clamped firmly and accurately.The original pressure sensor was replaced by a higher precision sensor with a measurement range from 0 to 20 kPa.The parameters in the software were adjusted accordingly.The accuracy and stability of the device were tested.Results The original device was improved as a small,delicate and easy to operate device with reliable clamps and visible change in its test parts.Accuracy testing showed that the reference error was very small,ranging from-0.30% to ＋0.29%.Stability testing showed the data obtained from the 5 groups tested at different time were （18 723±16）,（18 705±5）,（18 720±23）,（18 731±15）,（18 733±20） Pa,and there was no significant difference（P0.05）.Conclusion The improved device is suitable for detecting the tension strength of small tension membranaceous biomaterials such as tissue engineered skin.
出处
《第三军医大学学报》
CAS
CSCD
北大核心
2010年第9期904-907,共4页
Journal of Third Military Medical University
基金
国家高技术研究发展计划(863计划
2006AA02A121)
重庆市自然科学基金(CSTC2007BB5383)~~
关键词
组织工程
膜状生物材料
张力测试
环状夹具
tissue engineering
membranaceous biomaterial
tension measurement
circular clamping apparatus
