摘要
目的:探讨血浆同型半胱氨酸水平与脑梗死动脉粥样硬化的关系。方法:动脉粥样硬化性脑梗死患者88例(脑梗死组),同期健康体检者40例(对照组),根据颈动脉多普勒彩色超声检查结果将脑梗死组分为脑梗死A组(有斑块)和脑梗死B组(无斑块),将对照组分为对照组A(有斑块)和对照B组(无斑块)。测定研究对象血浆同型半胱氨酸水平,并进行比较。结果:脑梗死组血浆同型半胱氨酸水平和颈动脉斑块数均高于对照组,差异均有统计学意义(P<0.05);有斑块组同型半胱氨酸水平高于无斑块组,差异有统计学意义(P<0.05)。结论:血浆同型半胱氨酸水平与动脉粥样硬化和脑梗死密切相关,可能是动脉粥样硬化的危险因素之一。
Objective To investigate the relationship between plasma homocysteine and atherosclerosis in cerebral infarction.Methods Eighty-eight patients were chosen as the cerebral infarction group and other 40 healthy people as control group.According to the results of carotid Doppler ultrasonography,the cerebral infarction group was divided into two subgroups,cerebral infarction with carotid atherosclerotic plaque and cerebral infarction without plaque.And the controls were also divided into two subgroups,control with carotid atherosclerotic plaque and control without plaque.The levels of plasma homocysteine were measured and compared.Results The plasma level of homocysteine and the number of carotid atherosclerotic plaque were both significantly higher in the cerebral infarction group than those in control group（P〈0.05）.The level of homocysteine was higher in the carotid atherosclerotic plaque group than that in group without plaque（P〈0.05）.Conclusion Plasma homocysteine is closely related to atherosclerosis and cerebral infarction,and it may be one of the most important risk factors of carotid atherosclerotic.
出处
《中华实用诊断与治疗杂志》
2010年第5期465-466,共2页
Journal of Chinese Practical Diagnosis and Therapy
