摘要
目的 确定在孕２０ ～２８ 周治疗细菌性阴道病（ＢＶ） 能否降低有早产史孕妇早产发生率。 方法 在产前门诊对有早产史孕妇进行ＢＶ 筛查，对检出的患者随机分为应用灭滴灵和红霉素治疗及未加治疗组，随诊妊娠结局。 结果 在１７０ 例有早产史孕妇中，共检出ＢＶ８１ 例、检出率４７．６％ 。４１ 例患者接受灭滴灵及红霉素口服治疗；另４０ 例未予治疗。治疗组孕妇胎膜早破、早产及低出生体重儿发生率分别为２４ ％ 、２０ ％ 及１７ ％ ，低于未治疗组（ 分别为４８ ％ 、４０ ％ 及３５ ％ ）。 结论 中孕期筛查和口服灭滴灵及红霉素治疗细菌性阴道病可降低有早产史孕妇早产及胎膜早破发生率。
Objective To evaluate whether treatment of bacterial vaginosis during pregnancy with Metronidazole and Erythromycin reduces the incidence of preterm birth. Methods Women seeking prenatal care at 20～28 weeks of gestational age who had bacterial vaginosis were studied.Of 170 women with history of preterm birth,81 women,of which 41 were treated,were bacterial vaginosis positive and were followed up through delivery. Results The rate of preterm birth (<37 weeks) was 20% for treated patients and 40% for control.The rate of premature rupture of membrance was 24.4%for treated patients and 48% for control. Conclusion Treatment of bacterial vaginosis with Metronidazole and Erythromycin in women with bacterial vaginosis reduced preterm birth rate and premature rupture of membrance rate.
出处
《中华围产医学杂志》
CAS
1999年第1期10-11,共2页
Chinese Journal of Perinatal Medicine
关键词
阴道病
细菌性
早产
甲硝唑
红霉素
预防
Vaginosis,bacterial Labor,premature Metronidazole Erythromycin
