摘要
目的 探讨生殖道解脲支原体（ＵＵ） 和沙眼衣原体（ＣＴ） 感染与早产胎膜早破的关系。 方法 采用聚合酶链反应方法，对３０ 例早产胎膜早破（ＰＰＲＯＭ） 孕妇宫颈分泌物进行ＵＵ 和ＣＴ检测，并对分娩后的胎盘和胎膜分别进行ＵＵ 及组织病理学检查，同时分别选择３０ 例足月胎膜早破（ＰＲＯＭ）和４０ 例正常孕妇作对照。 结果 ＰＰＲＯＭ 孕妇宫颈分泌物ＵＵ 阳性率（７７ ％） 明显高于ＰＲＯＭ（４３ ％）（Ｐ＜ ０．０５） 和正常组（３０ ％）（ Ｐ＜ ０．０１） ；ＣＴ 阳性率（５３ ％） 高于ＰＲＯＭ（２３ ％ ）（ Ｐ＜０．０５）和正常组（１０ ％）（ Ｐ＜０ ．０１）；ＵＵ 和ＣＴ 同时感染的阳性率（４３ ％ ）高于ＰＲＯＭ（１３ ％ ）（Ｐ＜ ０．０５）及正常组（０ ％）（Ｐ＜０ ．０１）。胎盘ＵＵ 检出率在中、重度绒毛膜羊膜炎中明显增高（７１ ％）（Ｐ＜０ ．０１） 。结论 ＰＰＲＯＭ 的发生与ＵＵ 和ＣＴ感染有关。
Objective To explore the relationship between the genital infections with ureaplasma urealyticum(UU) and chlamydia trachomatis(CT) and the preterm premature rupture of membranes(PPROM). Methods 30 patients with PPROM (case group),30 patients with premature rupture of membranes(PROM)and 40 women with normal pregnancy(control group) were investigated as a case control study.The polymerase chain reaction(PCR) technique was used to detect UU DNA and CT DNA in samples from the secretion of cervix,and UU also was detected in the placentas.Placentas were examined for histological chorioamnionitis. Results The positive rate of UU in patients with PPROM(76.6%) was higher than those with PROM(43.3%)( P <0.05) and control group(30.0%)( P <0.01).The positive rate of CT in patients with PPROM (53.3%) was higher than those with PROM(23.3%)( P < 0.05 ) and control group(10%)( P <0.01).The positive rate of UU and CT in patients with PPROM( 43.3% ) was higher than those with PROM(13.3%)( P <0.05) and control group(0%)( P <0.01).The positive rate of UU in patients with the moderate or severe chorioamnionitis was higher than those without moderate or severe chorioamnionitis( P <0.01). Conclusion Preterm premature rupture of membranes is related to infections of UU and CT.
出处
《中华围产医学杂志》
CAS
1999年第1期15-17,共3页
Chinese Journal of Perinatal Medicine
关键词
沙眼衣原体
早产
胎膜早破
解脲支原体
Ureaplasma urealyticum Chlamydia trachomatis Labor,premature Fetal membranes,premature rupture
