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内皮素在肺间质纤维化发生发展中的作用 被引量：1

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摘要 肺间质纤维化（idiopathic pulmonaryfibrosis）是一种致病原因复杂、发病机制不清、缺乏有效治疗手段的致命性弥漫性肺间质疾病，其发病率及病死率逐年增高，确诊后平均存活期为2—4年，5年生存率仅为30％-50％。多种损伤因素均可单独或联合作用于肺脏，导致肺脏损伤与修复平衡失调，成纤维细胞和（或）细胞外基质沉积过度，最终形成肺纤维化。
作者 唐正梁 林庆艳
机构地区 黑龙江省医院南岗分院呼吸内科
出处 《中国基层医药》 CAS 2010年第9期1279-1280,共2页 Chinese Journal of Primary Medicine and Pharmacy
关键词 肺间质纤维化 内皮素 弥漫性肺间质疾病 细胞外基质沉积 生发 5年生存率 损伤与修复 成纤维细胞
分类号 R563 [医药卫生—呼吸系统]
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参考文献22

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二级参考文献43

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中国基层医药
2010年 第9期

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