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骨孤立性浆细胞瘤18例临床分析 被引量:5

Clinical analysis of 18 cases-with solitary bone plasmacytoma
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摘要 目的通过总结分析骨孤立性浆细胞瘤(SBP)的临床特点及治疗方法来提高其诊治水平。方法回顾分析5家医院1999年至2009年收治的18例SBP的临床资料,对其临床特点及治疗疗效进行总结。结果18例SBP患者年龄35~78岁,平均年龄54.2岁,男女比2.6:1。通过随访治疗1一10年,采用化放疗治疗的10例患者有8例生存,2例死于进展为多发性骨髓瘤(MM),单纯化疗或单纯放疗的8例患者中有1例因化疗相关并发症死亡,2例死于进展为MM。全部患者目前共有11例处于持续缓解状态(CCS),2例因进展为MM在积极治疗中,平均CCS时间为47-3个月。结论SBP是低度恶性肿瘤,化疗和放疗是其治疗的主要手段,化放疗相结合预后满意,部分患者可转化为MM。 Objective To improve the diagnosis level of solitary bone plasmacytoma (SBP) through analysing the clinical characteristics and therapy of this disease. Methods The clinical data of 18 cases were retrospectively analysis since 1999 in five hospitals, the clinical characteristics and therapeutic effect was summarized. Results The average age of 18 cases is 54.2 year (35-78), male were 1.6 times than female. 8 of 10 patients survived for 1-10 year after chemoradiotherapy, 2 of them progressed to multiple myeloma (MM) and died. 5 of 8 patients survived after only chemotherapy or radiotherapy. There were 11 cases of all patients in continue complete remission (CCS), the average CCS time was 47.3 months. Conclusion SBP is a type low-grade malignant tumor. Chemotherapy and radiotherapy is the main therapy. The patients can gain satisfactory prognosis with chemoradiotherapy, part of them can progress to MM.
出处 《肿瘤研究与临床》 CAS 2010年第4期222-224,共3页 Cancer Research and Clinic
关键词 孤立性浆细胞瘤 临床分析 治疗 随访 回顾性研究 Solitary bone plasmacytomas Clinical analysis Therapy Follow-up Retrospective studies
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参考文献9

  • 1Shih LY,Dunn P,Leung WM,et al.Comparison between extramedullary plasmacytoma and solitary plasmacytoma of bone.Br J Cancer,1995,71:128-133.
  • 2Dimopoulos MA,Moulopoulos LA,Maniatis A,et al.Solitary plasmacytoma of bone and asymptomatic multiple myeloma.Blood,2000,96:2037-2044.
  • 3黄稳定,肖建如.脊柱孤立性浆细胞瘤诊治进展[J].国际骨科学杂志,2008,29(3):156-158. 被引量:6
  • 4Coskun HS,Er O,Soyuer S,et al.Solitary plasmacytoma:experiences from Central Anatolia.lr J Med Sci,2005,174:33-36.
  • 5Tsangrw RW,Gospodarowiczmk MK,Pintiliem M,et al.Solitary plasmacytoma treated with radiotherapy:mi pact of tumor size on outcome.Int J Radiat Oncol Biol Phys,2001,50:113-120.
  • 6卢红阳,马胜林,郭勇,王晓稼,蔡菊芬.髓外浆细胞瘤四例报道并文献复习[J].肿瘤研究与临床,2006,18(10):696-697. 被引量:8
  • 7Dmi opoulos MA,Goldstein J,Fuller L,et al.Curability of solitary bone plamsacytoma.J Clin Oncol,1992,10:587-590.
  • 8Dimopoulos MA,Hamilos G.Solitary bone plasmacytoma and extramedullary plasmacytoma.Current Treatment Options Oncol,2002,27:255-259.
  • 9潘衍基,卫光宇,余丰文,冯彦林,刘德军.^(18)F-FDG PET与^(99)Tc^m-MDP显像对肿瘤骨转移的诊断价值[J].肿瘤研究与临床,2006,18(11):748-749. 被引量:3

二级参考文献48

  • 1张亚峰,杨惠林,刘晓峰,史勇,唐天驷.脊柱孤立性浆细胞瘤的诊断与治疗[J].中国脊柱脊髓杂志,2005,15(8):509-510. 被引量:4
  • 2Wax M K,Yun J,Omar R A,et al.Extramedullary plasmacytomas of the head and neck[J].Otolarygol Head Neck Surg,1993,109(5):877-885.
  • 3Miller F R,Lavertu P,Wanamaker J R,et al.Plasmacytoma of the head and neck[J].Otolarygol Head Neck Surg,1998,119(6):614-618.
  • 4Susnerwala S S,Shanks J H,Banerjiee S S,et al.Extramedullary plasm-acytoma of the head and neck region:clinic opathological correlation of 25 cases[J].Br J Cancer,1997,75(6):921-927.
  • 5Mock P M,Neal G D,Aufdemorte T B.Immunoperoxidase characteri-zation of extramedullary plasm-acytoma of the head and neck[J].Head Neck Surg,1987,9(6):356-361.
  • 6Mayr N A,Wen B C,Hussey D H,et al.The role of radiationtherapy in the treatment of solitary plasmacytoma[J].Radiother on Col,1990,17(4):293.
  • 7Knowling M A,Harwood A R,Bergsagel D E.Comparison of extramedullary plasmacytomas with solitary and multiple plasma cell tumors of bone[J].J Clin Oncol,1983,1(4):255.
  • 8Alexiou C,Kau R J,Dietzfelbinger H,et al.Extramedullary plasmacytoma:Tumor occurrence and therapeutic concepts[J].Cancer,1999,85(11):2305-2314.
  • 9Cook G J,Houston S,Rubens R,et al.Detection of bone metastases in breast cancer by 18F-FDG PET:differing metabolic activity in osteoblastic and osteolytic lesions[J].Clin Oncol,1998,16(10):3375-3379.
  • 10Yang S N,Liang J A,Lin F J,et al.Comparing whole body (18)F-2-deoxyglucose positron emission tomography and technetium-99m methylene diphosphonate bone scan to detect bone metastases in patients with breast cancer[J].Cancer Res Clin Oncol,2002,128(6):325-328.

共引文献14

同被引文献46

  • 1刘卫金,孙清荣,王文献.股骨孤立性浆细胞肉瘤1例[J].第三军医大学学报,2004,26(18):1698-1698. 被引量:2
  • 2唐勇,李晓君,刘晋新,成官迅.浆细胞瘤的CT、MR表现[J].实用医技杂志,2005,12(03B):703-705. 被引量:7
  • 3Soutar R,Lucraft H,Jackson G,刘淑艳,薛永权.孤立性骨骼浆细胞瘤和孤立性髓外浆细胞瘤的诊断和处理指南[J].国外医学(输血及血液学分册),2005,28(4):289-294. 被引量:8
  • 4江波,陈应明,孟悛非,潘碧涛.单倍剂量三维动态对比增强MR血管成像诊断肢体软组织血管瘤的价值[J].中华放射学杂志,2007,41(1):59-63. 被引量:8
  • 5Subhas N,Bauer TW,Joyee MJ, et al. The "mini brain" appearance of plasmacytoma in the appendicular skeleton[J]. Skeletal Radiol,2008,37(8) :771-774.
  • 6Dimopoulos MA, Moulopoulos LA, Maniatis A, et al. Solitary plasmacytoma of bone and asymptomatic multiple myeloma[J]. Blood, 2000,96 (6) : 2037-2044.
  • 7Rodallec MH, Feydy A, Larousserie F, et al. Diagnostic imaging of solitary tumors of the spine: what to do and say[J]. Radio- Graphics,2008,28(4) : 1019-1041.
  • 8Major NM, Helms CA, Richardson WJ. The "mini brain": plasmacytoma in a vertebral body on MR imaging[J]. AIR, 2000, 175 (1) :261-263.
  • 9Zawin JK,Jaramillo D. Conversion of bone marrow in the homerus,sternum, and clavicle: changes with age on MR images[J].Radiology, 1993,188(1) : 159-164.
  • 10Ly J Q,Sandiego JW,Beall DP. Plasmacytoma of the proximal humerus[J]. Clin Imaging,2005,29(5) :367-369.

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