摘要
研究姜黄素对H22荷瘤小鼠红细胞膜唾液酸水平和封闭度的影响.建立小鼠H22肿瘤模型,方法采用对照比色法测定H22小鼠红细胞膜唾液酸水平和封闭度.姜黄素可剂量依赖性地提高荷瘤小鼠红细胞膜唾液酸水平和封闭度,且差异显著(P<0.05).姜黄素可能是通过提高H22荷瘤小鼠红细胞膜SA水平和封闭度,进而提高机体的免疫功能而达到抗肿瘤目的.
To study the effect of curcumin on sialic acid（SA） and blocking degree of erythrocyte membrane in H22 tumor-bearing mice.Using chromatometry to determine the erythrocyte membrane sialic acid and erythrocyte membrane blocking degree.Curcumin could increase erythrocyte membrane sialic acid level and heighten erythrocyte membrane blocking degree in a dose-dependent manner in H22 tumor-bearing mice significantly（P0.05）.Curcumin can be adopted to improve erythrocyte membrane sialic acid and erythrocyte membrane blocking degree,so as to resume the tumor-bearing mice red blood cell immune function and thus achieve the purpose of the anti-tumor.
出处
《哈尔滨商业大学学报（自然科学版）》
CAS
2010年第2期133-135,共3页
Journal of Harbin University of Commerce：Natural Sciences Edition
基金
黑龙江省自然科学基金项目(D2004-19)
黑龙江省教育厅项目(10551086)
关键词
姜黄素
红细胞膜
封闭度
唾液酸
curcumin
erythrocyte membrane
blocking degree
sialic acid（SA）
