摘要
目的 回顾性分析潍坊地区213例宫颈癌患者的临床资料,探讨近期子宫颈癌的临床特点及治疗方法.方法 回顾性分析213例宫颈癌患者的发病年龄、HPV感染情况、临床分期、治疗方式及术后病理结果.结果 213例患者年龄（45.32±11.2）岁,中位数年龄为44岁.年轻宫颈癌（≤35岁）的构成比为22.07%.≤35岁宫颈癌患者的HPV 阳性率为65%,较〉35岁者明显升高,后者为32%.Ⅱ期、Ⅲ期及Ⅰ期、Ⅲ期间患者的平均年龄均有显著性差异（P＜0.05）.213例患者中,12例患者未行手术,其余患者均经手术治疗.结论 潍坊地区近5年宫颈癌具有明显年轻化、临床分期早的趋势,且与HPV感染有相关性.提倡对所有有性生活3年以上的女性进行普查,加强对HPV感染高危人群的监测、随访,以便及时预防癌前病变和早期宫颈癌.对已确诊的年轻宫颈癌患者进行预后估计,并采取相应的综合治疗措施以改善患者的预后和生活质量.
Objective To retrospectively analyze the clinical data of 213 cases of cervical cancer in welfang region,and to investigate the clinical characteristic and treatment of cervical cancer in recent years. Methods The clinical data of 213 cases with cervical cancer admitted in the affiliated hospital of Weifang medical college and Weifang people’s hospital from January 2004 to December 2008 was analyzed retrospectively, including the patients age, test of HPV, clinical stage, treatment and postoperative pathological diagnosis. Results The average age of the patients was 45.32±11. 2. The median age was 44. The constituent ratio of the young patients（ ≤35 years） was 22.07%. The positive rate of HPV infection in women under the age of 35 was significantly higher than that in women over 35 years old （ 65% versus 32% ）. As the clinical stage progress,the average age was increased accordingly. There was a significant difference in the patients age between stage Ⅰ and of stage Ⅲ （P = 0.036 ） , stage Ⅱ and stage Ⅲ（ P= 0. 023 ）. Except for the two patients, all the others were treated with surgery. Conclusion There is an obvious trend that the patient was younger and clinical stage was earlier in Weifang region in recent 5 years. For the younger patients, the disease is closely related with HPV infection, h should be advocated that, for all sexually active women over 3 years,the census should be performed. Monitoring and follow-up of the women with HPV infection should be strengthened, so as to prevent precancerous lesion and early cancer timely. Prognostic evaluation should be taken for those young patients. Comprehensive measures should be taken to improve the prognosis and the quality of life.
出处
《潍坊医学院学报》
2010年第1期17-19,共3页
Acta Academiae Medicinae Weifang
