摘要
目的：探讨脊柱退变性疾病体液因素的改变及其意义。方法：利用放免测定法对２３例健康成人和４０例颈椎病，腰椎间盘突出症患者血浆血管紧张素Ｉ（ＡｎｇＩ）含量进行了检测分析。结果：患者组血浆ＡｎｇＩＩ含量为６９１±３２５ｐｇ／ｍｌ，显著高于正常（Ｐ＜０００１）；其中颈椎病为６８７±３４７ｐｇ／ｍｌ（ｘ＋ｓｄ），腰椎间盘突出症患者为７０１±３１５ｐｇ／ｍｌ（ｘ＋ｓｄ），均显著高于正常，而两者之间无显著差异（Ｐ＞００５）结论ＡｎｇＩ分泌的增加是机体交感神经纤维的兴奋效应，并对这一效应的意义作了探讨。
Aim:To determine the level of angiotenstin II in blood of patients with spine disorder and discuss the relationship.Methods:Using radioimmunoassay ,we measured the level of angiotensin Ⅱ in patients with cervical spondylosis(n=19)or prolapsed lumbar intervertebral disc (n=21).We also determined the normal people(n=23).Results:The patients' level of angiotenstin II was 69 1±32 5pg/ml which was higher than control group'(40 2±12 0pg/ml) statistically significant ( P <0 001) The level of patients with cervical spondylosis was 68.7±34 7pg/ml and with prolapsed lumbar intervertebral disc was 68.7±31 5pg/ml,higher than that of control group significantly respectively.The differance between groups was not remarkable( P >0 05) Conclusions:Spinal disorder cause secretion of AngII following sympathetic nerve stimulated. AngII is protective to spine disorder.
出处
《颈腰痛杂志》
1999年第1期14-15,共2页
The Journal of Cervicodynia and Lumbodynia
关键词
颈椎病
腰椎间盘突出症
血管紧张素Ⅱ
病理学
Cervical spondylosis\ Prolapsed lumbar intervertebral disc\ Angioterstin II
