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冠心康对实验性高脂血症及血液流变学的影响 被引量:5

Effects of Guanxinkang Granule on Experimental Hyperlipemia and Hemorrheology
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摘要 探讨冠心康颗粒剂对小鼠实验性高脂血症及大鼠血液流变学的影响,结果表明冠心康能明显抑制TritonWR-1339所致小鼠TG、TC的升高,增强血瘀大鼠红细胞变形能力,降低全血比粘度和血浆比粘度,降低五羟色胺的含量。 Effects of guanxinkang granule(GG)on experimental hyperlipemia in mice and hemorrheology in rats were studied.The results showed that GG could remarkably lower the increased of serum TC and TG levels induced by Triton WR 1339.As for the rats with blood stasis,GG was observed to possess remarkable enhancing effects on erythrocyte deformability,decrease ηB、ηP,and lower the level of 5 HT.In addition,GG could significantly dilate micrangium and improve blood flow rate in normal mice.
出处 《中国实验方剂学杂志》 CAS 1999年第2期24-26,共3页 Chinese Journal of Experimental Traditional Medical Formulae
关键词 冠心康 血液流变学 高脂血症 Guanxinkang granule,hemorrheology,hyperlipemia
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参考文献2

  • 1杨甲禄.一种简便、快速筛药的高脂血症模型,Triton WR1339对小鼠血清及肝脏脂质的影响[J].中国药理学通报,1987,3(2):124-127.
  • 2时其煌.冠心Ⅱ号对家兔血小板释放5-HT含量和超微结构的影响[J].中西医结合杂志,1981,(1):90-90.

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