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2种方案治疗难治性抑郁症的成本-效果分析 被引量:1

Cost-effectiveness Analysis of 2 Kinds of Regimens for Treatment-resistant Depression
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摘要 目的:对文拉法辛联合喹硫平治疗难治性抑郁症进行药物经济学评价。方法:74例难治性抑郁症患者随机分为试验组(n=38)与对照组(n=36),采用汉密顿抑郁量表(HAMD)分别在入组时与第12周末评估临床疗效,于12周末统计成本,并进行成本-效果分析。结果:试验组与对照组人均成本分别为1688.69元与1487.22元,HAMD评分减少量分别为14.5与10.2,成本-效果比分别为116.46与145.81。结论:2种治疗方案中,文拉法辛联合喹硫平是治疗难治性抑郁症较经济方案。 OBJECTIVE:To evaluate the pharmacoeconomics effectiveness of venlafaxine combined with quetiapine in the treatment of treatment-resistant depression.METHODS:74 patients with treatment-resistant depression were randomly divided into treatment group(n=38) and control group(n=36).Clinical efficacies of 2 groups were evaluated at baseline and the end of 12 weeks treatment using Hamilton Rating Scale for Depression(HAMD).The total cost of the two groups was calculated and cost-effectiveness analysis was carried out.RESULTS:The per capita cost of treatment group and control group were 1 688.69 and 1487.22 yuan.The HAMD reduction score of 2 groups were 14.5 and 10.2 and the C/E of 2 groups were 116.46 and 145.81,respectively.CONCLUSION:Venlafaxine combine with quetiapine is more economical and practical than venlafaxine alone in the treatment of treatment-resistant depression.
出处 《中国药房》 CAS CSCD 北大核心 2010年第20期1908-1909,共2页 China Pharmacy
关键词 难治性抑郁症 文拉法辛 喹硫平 成本-效果分析 Treatment-resistant depression Venlafaxine Quetiapine Cost-effectiveness analysis
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