摘要
目的:研究血压和血糖与老年人不同死因之间的关系,为临床预防提供指导方向。方法:在资料相对完整的死亡患者883例中,选择年龄>60岁的501例作为调查对象。其中,糖尿病人群180例,分为:糖尿病高血压组(DM/HT组,108例,占60.14%)和糖尿病非高血压组(DM组,72例,39.86%);非糖尿病人群321例,分为:非糖尿病高血压组(HT组,130例,40.50%)和非糖尿病非高血压组(非DM/HT组,191例,59.50%)。观察各组患者的性别、年龄、血压、血糖和死因(主要是指心脑血管意外、肿瘤、感染和尿毒症)。结果:①老年人高血压患病率:非糖尿病40%,糖尿病60%,且男性好发;②DM/HT、HT脑出血是第一位死因,超过30%;DM、非DM/HT血管意外仅20%,且以梗塞性疾病为主;③DM、非DM/HT恶性肿瘤是第一位死因;高血压与肿瘤无关(肾梭形细胞癌除外);④糖尿病2个亚组感染患病率高;⑤DM/HT组、HT组尿毒症患病率高于其余两组;⑥多元回归分析后,收缩血压、舒张血压与心脑血管意外相关,与肿瘤、感染无关,前者与尿毒症也有相关性;空腹血糖与4种死因均相关。结论:血压和血糖与老年人不同死因之间有相关性,应针对不同人群进行相应疾病预防。
Objective:To study the relationship between blood pressure,blood glucose and the different causes of death in elderly,and then provide a guidance for clinical prevention.Methods:883 dead patients with relatively complete information were investigated,to choose cases aged over 60 years as subjects.The 501 patients were divided into two groups:180 diabetics and 321 non-diabetics,and then were subgrouped according to blood pressure:diabetes /hypertension group(DM /HT,108 cases,60.14%),diabetes group(DM,72 cases,39.86%),hypertension group(HT,130 cases,40.50%),non diabetes/hypertension group(non-DM/HT,191 cases,59.50%) respectively.Sex,age,blood pressure,blood glucose and cause of death were observed in each group.Results:① The incidence of hypertension in the elderly were 40% in non-diabetes and 60% in diabetes,and higher in men;②Cerebral hemorrhage was the first cause of death(more than 30%) in DM/HT and HT groups;meanwhile vascular accident,mostly infarction was only 20% in DM and non-DM /HT groups;③Malignant tumors was the first cause of death in DM and non-DM/HT groups,and meanwhile it was not related with hypertension(except for renal spindle cell carcinoma);④There was a high prevalence of infection in the two sub-groups of diabetes;⑤The uremia prevalence was higher in DM /HT group and HT group than in the other two subgroups;⑥Multiple regression analysis showed systolic blood pressure and diastolic blood pressure were associated with cardio-cerebral vascular accident,unrelated to tumors and infection,the systolic blood pressure was also associated with uremia;fasting blood glucose were associated with the four causes of death.Conclusions:There was a relationship between blood pressure and blood glucose with the different causes of death in the elderly,and we should carry into disease prevention accordingly to different groups.
出处
《南京医科大学学报(自然科学版)》
CAS
CSCD
北大核心
2010年第5期692-696,共5页
Journal of Nanjing Medical University(Natural Sciences)
基金
江苏省医学领军人才基金
关键词
血压
血糖
死因
老年
blood pressure
blood
glucose
death
causes
elderly