摘要
目的探讨血清γ-谷氨酰基转移酶(GGT)、丙氨酸氨基转移酶(ALT)对2型糖尿病早期诊断的临床应用价值。方法采用Roche Modu lar全自动生化分析仪及配套试剂检测200例2型糖尿病患者(男、女各100例)及200名正常对照者的血清葡萄糖(G lu)、GGT和ALT水平,并进行统计分析。结果 2型糖尿病患者男性及女性的G lu、GGT水平与对照组比较,差异均有统计学意义(P<0.05),而ALT则无差异;男性和女性2型糖尿病患者中GGT浓度超出参考区间的百分率分别是13%和16%,明显高于对照组。结论 GGT对于2型糖尿病的早期诊断有一定意义。
Objective To investigate the clinical application value of serum gamma-glutamyltransferase（GGT） and alanine aminotransferase（ALT） for the early diagnosis of type 2 diabetes mellitus.Methods 200 patients with type 2 diabetes mellitus were enrolled in experiment group（100 males and 100 females）.200 healthy subjects were enrolled as control group.The levels of serum glucose（Glu）,GGT and ALT of patients and healthy subjects were detected by Roche Modular automatic biochemistry analyzer system and the results were analyzed statistically.Results The difference of serum Glu and GGT between experiment group and control group had statistical significance（P 0.05）.There was no difference of ALT between experiment group and control group.The abnormality rates of GGT among male and female patients with type 2 diabetes mellitus were 13% and 16% respectively,which were higher than those in control group.Conclusions GGT may be a marker for the early diagnosis of type 2 diabetes mellitus.
出处
《检验医学》
CAS
北大核心
2010年第5期349-351,共3页
Laboratory Medicine
