摘要
目的观察米索前列醇对妊娠期高血压疾病患者产后出血的影响。方法选择住院分娩妊娠期高血压疾病患者168例,随机分为2组。观察组86例,于胎儿娩出后立即直肠内置入米索前列醇400μg;对照组82例,胎儿娩出后立即臀部肌内注射缩宫素20U。分别观察产后2h出血量、第3产程时间、产后出血发生率及不良反应。结果观察组产后2h出血量及第3产程时间均低于对照组,差异有统计学意义(P<0.01)。结论米索前列醇直肠给药能有效地防治妊娠期高血压疾病产后出血,且用药简单、安全,值得临床推广。
Objective To observe the influence of misoprostol in preventing postpartum hemorrhage on hypertensive disorders in pregnancy. Methods 168 cases of hypertensive disorders in pregnancy patients were randomly divided into obser- vation group of 86 eases and control group of 82 eases. The observation group immediately after the baby was delivered to inser- ting misoprostol 400μg in the rectum wall office. The control group immediately after the baby was delived to intramusele injection of oxytoein 20U. Observed the third stage of labortime ,2-hour blood volume, postpartum hemorrhage rate and side reaction. Results 2-hour blood volume, postpartum hemorrhage rate and the third stage of labor time in observation group were lower than that in control group. The differences were statistically significant （ P 〈 0.01 ）. Conclusion Misoprostol rectum to medi- cine to prevent postpartum hemorrhage on hypertensive disorders in pregnancy is a safe and simple method.
出处
《临床合理用药杂志》
2010年第10期30-31,共2页
Chinese Journal of Clinical Rational Drug Use
关键词
米索前列醇
妊娠期高血压疾病
产后出血
直肠给药
Misoprostol
Hypertensive disorders in pregnaney
Postpartum hemorrhage
Rectum to medieine.
