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抗结核药物新剂型-异烟肼药质体的研究 被引量:2

The New Dosage Form of Anti-tuberculosis Drug-Isoniazid Pharmacosomes
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摘要 药质体是基于脂质前药的自组装药物传递系统之一,它作为一种新的药物传递技术,载药量大、稳定性好、有靶向性和控释性。抗结核药物异烟肼制备成药质体能靶向巨噬细胞,提高药物渗透性。本文对药质体概念、特性、目前研究状况和异烟肼制备成药质体前景进行综述。 Pharmacosomes are one of the self-assembled drug delivery systems(SADDSs), and it displays high drug loading, more stable, targeted and controlled as a new drug delivery technology. The anti-tuberculosis drug isoniazid pharmacosomes was prepared, can improve drug permeability and target macrophage. The concepts, characteristics, Current research situation and the preparation prospect of isoniazid pharmacosomes are introduced.
出处 《国外医药(抗生素分册)》 CAS 2010年第3期110-113,共4页 World Notes on Antibiotics
关键词 自组装药物传递系统 药质体 异烟肼 SADDSs pharmacosomes isoniazid
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参考文献18

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二级参考文献46

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