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单纯21三体染色体异常的急性白血病9例 被引量:4

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摘要 21号染色体三体(+21)是人类肿瘤中最常见的染色体异常之一。在急性髓系白血病(AML)患者中,+21是继8号染色体三体后的第二常见染色体三体。然而,在多数患者中,+21往往与其他染色体异常同时存在,包括染色体数目和(或)结构异常。单纯+21染色体异常少见,国外报道AML和骨髓增生异常综合征(MDS)伴单纯+21染色体异常发生率只占0.3%。
出处 《中华血液学杂志》 CAS CSCD 北大核心 2010年第5期347-348,共2页 Chinese Journal of Hematology
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  • 1Heim S,Mitelman F.Numerical chromosome aberrations in human neoplasia.Cancer Genet Cytogenet,1986,22:99-108.
  • 2Mitelman F,Heim S,Mandahl N.Trisomy 21 in neoplastic cells.Am J Med G enet Suppl,1990,7:262-266.
  • 3Cortes JE,Kantarjian H,O'Brien S,et al.Clinical and prognostic significance of trisomy 21 in adult patients with acute myelogenous leukemia and myelodysplastic syndromes.Leukemia,1995,9:115-117.
  • 4Gallego M,Solé F,Acín P,et al.A new case of trisomy 21 in a patient with an acute nonlymphocytic leukemia (M5b).Cancer Genet Cytogenet,1997,95:213-214.
  • 5Wan TS,Au WY,Chan JC,et al.Trisomy21 as the soleacquirad karyotypic abnormality in acute myeloid leukemia and myelodysplastic syndrome.Leuk Res,1999,23:1079-1083.
  • 6Hasle H,Clemmensen IH,Mikkelsen M.Risks of leukaemia and solid tumours in individuals with Down's syndrome.Lancet,2000,355:165-169.
  • 7Shen JJ,Williams BJ,Zipursky A,et al.Cytogenetic and molecular studies of Down syndrome individuals with leukemia.Am J Hum Genet,1995,56:915-925.
  • 8Wei CH,Yu IT,Tzeng CH,et al.Trisomy 21 in acute myeloid leukemia.Cancer Genet Cytogenet,1996,86:177-180.
  • 9Kondo H,Kobayashi A,Iwasaki H.Trisomy 21 as the sole acquired karyotypic abnormality in an adult patient with CD7-positive acute myeloid leukemia.Cancer Genet Cytogenet,2001,127:77-79.
  • 10Yamamoto K,Nagata K,Hamaguchi H.A new case of CD7-positive acute myeloblastic leukemia with trisomy 21 as a sole acquired abnormality.Cancer Genet Cytogenet,2002,133:183-184.

同被引文献26

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  • 5张丽君,王平平,卢香兰,何娟,李艳,翟明.荧光原位杂交检测急性髓性白血病21号染色体复杂核型异常[J].中华医学杂志,2006,86(48):3393-3396. 被引量:1
  • 6Barbara P. Rattner,Timur Yusufzai,James T. Kadonaga.HMGN Proteins Act in Opposition to ATP-Dependent Chromatin Remodeling Factors to Restrict Nucleosome Mobility[J]. Molecular Cell . 2009 (5)
  • 7Nyla A.Heerema,Susana C.Raimondi,James R.Anderson,JaclynBiegel,Bruce M.Camitta,Linda D.Cooley,Paul S.Gaynon,BetsyHirsch,R. EllenMagenis,LorisMcGavran,ShivanandPatil,Mark J.Pettenati,JeanettePullen,KathleenRao,DianeRoulston,Nancy R.Schneider,Jonathan J.Shuster,WarrenSanger,Maxine J.Sutcliffe,Petervan Tuinen,Michael S.Watson,Andrew JCarroll.Specific extra chromosomes occur in a modal number dependent pattern in pediatric acute lymphoblastic leukemia[J]. Genes Chromosom. Cancer . 2007 (7)
  • 8Hans D. Menssen,Jan M. Siehl,Eckhard Thiel.Wilms Tumor Gene ( WT1 ) Expression as a Panleukemic Marker[J]. International Journal of Hematology . 2002 (2)
  • 9Cuneo A,van Orshoven A,Michaux JL,et al.Morpholosic,im-munologic and cytogenetic studies in erythroleukaemia:evidence formultilineage involvement and identification of two distinct cytoge-netic-clinicopathological types. British Journal of Haematology . 1990
  • 10Kasyan Armen,Medeiros L Jeffrey,Zuo Zhuang,Santos Favio P,Ravandi-Kashani Farhad,Miranda Roberto,Vadhan-Raj Saroj,Koeppen Hartmut,Bueso-Ramos Carlos E.Acute erythroid leukemia as defined in the World Health Organization classification is a rare and pathogenetically heterogeneous disease. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc . 2010

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