摘要
目的用功能磁共振成像(fMRI)方法观察补法和泻法针刺足三里穴对大脑作用的中枢机制。方法选取32名健康右利手志愿者,对11名受检者用补法电针刺激右侧足三里穴(ST36)、11名用泻法电针刺激ST36、10名电针刺激右侧足三里穴同一水平向外2～3cm处。同时行全脑fMRI扫描;用SPM2软件进行图像后处理。结果电针结束后5min,泻法组的脑区激活不明显,而补法组平均信号升高的脑区主要有双侧尾状核头部、丘脑、左侧岛叶、扣带回及小脑齿状核。电针结束后20～30min期间两组脑区的激活最为明显,均激活左侧的丘脑、中央旁小叶、中央前回、颞中回、额中回、岛叶、双侧尾状核头部、小脑半球、前、后扣带回;两组激活区域大致相同,但补法组激活的脑区范围更广、强度更大。针刺假穴组只激活中央旁小叶及小脑半球。结论补、泻手法针刺足三里穴均能激活边缘系统、辅助运动区、灰质结构等脑区,而应用补法能更早、更强烈地激活上述脑区。
Objective To explore the central mechanisms when induced by acupuncture at ST36 using different needling techniques with functional magnetic resonance imaging （fMRI）. Methods Thirty-two healthy young volunteers were enrolled in the experiment. Eleven volunteers accepted acupuncture at ST36 using reinforcing techniques for electroacupuncture （EA）,11 accepted acupuncture using reducing techniques for EA,and the rest 10 accepted acupuncture at sham EA. The data of fMRI were collected and analyzed with statistical parametric mapping （SPM2） after real EA at ST36 or sham EA in right leg. Results Five minutes after acupuncture,fMRI data of reinforcing group demonstrated significant activation in the bilateral caudate nucleus,thalamus,left insula,cingulate gyrus,dentate body of cerebellum. From 20 to 30 minutes after acupuncture,fMRI data demonstrated significant activation of true acupuncture groups in the left thalamus,paracentral lobule,gyrus precentralis,middle temporal gyrus,middle frontal gyrus,insula,bilateral caudate nucleus,hemisphaerium cerebelli,anterior and posterior cingulate gyrus. The signal of the reinforcing group for EA was stronger than the reducing group for EA. Acupunture of the false point activated the paracentral lobe and the hemisphere of cerebellum only. Conclusion Stimulation of acupoint ST36 with acupuncture activated different parts of the autonomic nerve system,including imbic system,supplementary motor area,grey matter,etc. Reinforcing technique for EA is better than reducing technique at ST36.
出处
《中国医学影像技术》
CSCD
北大核心
2010年第4期635-638,共4页
Chinese Journal of Medical Imaging Technology
关键词
磁共振成像
脑
针刺
Magnetic resonance imaging
Brain
Acupuncture
