摘要
目的探讨血清癌胚抗原(CEA)、糖链蛋白199(CA199)、铁蛋白(SF)联合检测在胃癌中的临床价值。方法采用化学发光法,检测92例胃癌患者和40例胃良性疾病患者血清中CEA、CA199、SF浓度值。结果胃癌组血清中CEA、CA199、SF浓度均显著高于对照组(P<0.05),联合检测的灵敏度(92.4%)和准确度(87.9%)均明显高于单项检测。结论血清CEA、CA199、SF联合检测可以提高胃癌诊断的准确度和灵敏度,为临床对胃癌的早期诊断提供重要的实验室依据。
Objective To explore clinical valur of combination assay of serum CEA,CA199 and SF in gastric cancer.Methods The CEA,CA199 and SF contents of 92 cases of gastric carcinoma and 40 cases of benign gastric disease were detected by chemilumin escence immunoassay.Results The contents of serum CEA,CA199 and SF in gastric carcinoma patients were significant higher than that in healthy controllers（P〈0.05）.The sensitivity（92.4%） and accuracy（87.9%） of the combined determination were significant higher than single assay.Conclusion The sensitivity and accuracy of the combined determination of serum CEA,CA199 and SF in gastric carcinoma are improved and might provide valuable laboratory proof for early diagnostic in gastric carcinoma.
出处
《国际检验医学杂志》
CAS
2010年第4期345-345,348,共2页
International Journal of Laboratory Medicine
关键词
胃肿瘤
癌胚抗原
CA-19-9抗原
铁蛋白
实验室技术和方法测
stomach neoplasms carcinoembryonic antigen CA-19-9 antigen ferritin laboratory techniques and procedures
