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股骨头坏死与基因遗传多态性 被引量:10

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摘要 股骨头坏死(ONFH)系遗传易感因素和危险因素共同作用的多因素疾病,研究证实多种与凝血纤溶状态、脂质代谢、血管再生及激素代谢等相关的基因遗传多态性均与之发生存在显著相关性。ONFH基因遗传多态性相关研究,为ONFH易感人群筛查、早期诊断和早期干预提供了重要理论依据。更大规模、更加深入的研究以及实验技术的完善,将成为今后研究的方向。
作者 尹思 张长青
出处 《国际骨科学杂志》 2010年第3期178-180,189,共4页 International Journal of Orthopaedics
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