摘要
目的:探讨术前预防性化疗对子宫颈癌治疗的临床效果及意义,为子宫颈癌的综合治疗提供参考。方法:142例子宫颈癌患者,随机分为综合组及对照组,对照组采用常规手术治疗,综合组手术前后采用CP方案进行预防性化疗,分析两组患者根治切除率、术中淋巴结阳性率、术后复发转移率随访期内生存率。结果:综合组手术根治切除率为98.6%,对照组为94.4%,综合组根治切除率高于对照组,综合组淋巴结阳性率为23.9%,复发转移率为4.23%,对照组淋巴结阳性率为25.4%,复发转移率为8.45%,综合组低于对照组,两组患者随访期内生存率无明显差别。结论:预防性化疗能够改善宫颈癌的手术切除效果、降低患者的术后复发及转移风险。
Objective：To explore the clinical effect of chemoprophylaxis to operations and prognosis on uterine cervix cancer（UCC）,and provide reference for combined therapy.Methods：142 cases of patients with UCC were randomly divided into divid into combined therapy group（TG） and control group（CG）,all patients recived conventional operations,the patients in TG received additional chemoprophylaxis with Cytoxan and Platinol（CP）,and total excision rate,positive rate ofnodus lymphaticus,relapse and metastasis rate,survival rate were analysized. Results：total excision rate was 98.6% in TG and 94.4% in CG.total excision rate was higher in TG,positive rate of nodus lymphaticus was 23.9% in TG and 25.4% in CG,relapse and metastasis rate was 4.23% in TG and 8.45 in CG,those was lower in TG.the survival rate were identical between TG and CG.Conclusions：chemoprophylaxis could improve total excision rate on UCC,and to lower risk relapse and metastasis.
出处
《中国医药导刊》
2010年第4期544-545,共2页
Chinese Journal of Medicinal Guide
关键词
子宫颈癌
预防性化疗
根治切除
淋巴结
Uterine Cervix Cancer
Chemoprophylaxis
Total Excision
Nodus Lymphaticus
