摘要
目的:了解新建医院感染病原菌的分布和耐药性,为临床合理用药提供依据。方法:利用WHONET5.4软件分析2005～2008年自我院住院及门诊患者分离细菌的种类,分布及MIC和K-B法药敏试验数据。结果:所分离出的3081株病原菌中,革兰阴性菌占71%,革兰阳性菌占21%。真菌占8%。铜绿假单胞菌,大肠埃希菌,鲍曼不动杆菌,肺炎克雷伯菌,凝固酶阴性葡萄球菌,金黄色葡萄球菌,白色假丝酵母菌等是主要的医院感染菌。革兰阴性菌除鲍曼不动杆菌,铜绿假单孢菌外,对亚胺培南、美洛培南、哌拉西林/他唑巴坦、头孢派酮/舒巴坦的耐药率<10%。结论:临床应了解我院细菌对抗生素的耐药性特点,科学合理选用抗生素。
Objective： To investigate the distribution and the antimicrobial resistance of the bacteria in our hospital during 2005-2008. Methods：Clinical isolates of pathogenic bacteria were collected and indentified by VITEK2. Antimicrobial susceptibility of MIC were tested by VITEK2,and K-B method if necessary. The data were analyzed by WHONET 5.4 soft ware. Results：Of the 3081 pathogenic bacteria ,71% were Gram stain negative,21% were Gram stain positive and 8% were fungus. Among them Ps. aeruginosa, Esch.coli, Aci.baumannii, K.penum. pneumoniae, Coagulase negative staphylococcus, Staph.auteus and Candida albicans were the most frequent pathogenic bacteria of nosocomial infection. Most Gram stain negative bacteria except for Aci.baumannii and Ps. aeruginosa,the resistance rates to each of the antimicrobial agents including Imipenem, Meropenem, Piperacillin/Tazobactam, Cefoperazone/Sulbactam were lower than 10%. Conclusions：Doctors should be well aware of the surveillance of antimicrobial resistance and take rational antimicrobial therapy.
出处
《中国医药导刊》
2010年第5期828-828,831,共2页
Chinese Journal of Medicinal Guide
关键词
医院感染
抗生素
耐药性
Nosocomial infection
Antibiotics
Antimicrobial resistance
