摘要
宫颈癌相关肿瘤标志物是宫颈癌组织和细胞由于癌基因及其产物的异常表达所产生的抗原和生物活性物质,包括蛋白质、酶、激素、癌基因产物等。近年来肿瘤标志物成为肿瘤基础和临床应用的一个十分活跃的领域。其对宫颈癌的辅助诊断、判别类型、估计预后、评价疗效、定位诊断、靶向治疗等均具有重要指导意义。目前与宫颈癌有关的生物标记物有数十种,包括人乳头状瘤病毒感染、细胞周期调节蛋白、细胞凋亡相关因子等。随着研究的深入,这些生物标记物在临床上已显示出广阔的应用前景。
Tumor markers are bioactive substance and antigen produced by cervical cancer tissue and cell because of oncogene abnormal expression including protien,enzyme and hormone et al.In recent years,tumor marker has been one of the most active areas in basic research and clinical investigation of oncology.A variety of tumor markers have been shown to have potential applications in accessory diagnosis,clinicaltyping,prognosis,and therapeutic respons and target therapy of cervical cancer.Now tens of markers reported are related to cervical cancer,including HPV infection,cell cycle regulatory protein,apoptosis,and other related factors.With the in-depth study,these markers in clinical practice has shown broad prospects.
出处
《现代生物医学进展》
CAS
2010年第9期1777-1779,共3页
Progress in Modern Biomedicine
