摘要
目的比较2种用药方案治疗带状疱疹的临床疗效、安全性及预防后遗神经痛的临床效果。方法筛选出的180例病例根据治疗方案不同分为2组:第一组(治疗组)92例口服伐昔洛韦片+复方甘草酸苷片(美能片)、第二组(对照组)88例口服伐昔洛韦片。观察临床症状和体征、不良反应和后遗神经痛的发生率,对比疗效。结果治疗组症状和体征的改善时间比对照组短,其中以止痛时间缩短最为显著(P<0.01),后遗神经痛发生率第一组明显低于第二组(P<0.05),两组的疗效及不良反应发生率无显著性差别(P>0.05)。结论口服伐昔洛韦片+复方甘草酸苷片(美能片)治疗带状疱疹是一种安全、有效、依从性好的用药方案。
Objective To compare the efficacy, security and prevention residual neuralgia in treating herpes zoster with two drug therapy programs. Methods 180 patients with herpes zoster were randomly divided into 2 groups, the first group（ treatment group）92 patients were given valaciclovir hydrochloride tablets ＋ compound glycyrrhizin tablets to treat, the second group （ control group） 88 patients were given valaciclovir hydrochloride tablets to treat, symptoms, signs, adverse reaction and the rate of residual neuralgia were observed. Resuits The regression time of the symptoms and signs in the treatment group were shorter than that of the control group, especially significant variance in the time of relieving pain （ P 〈 0.01 ）. The incidence rate of residual neuralgia in the treatment group was significantly lower than that of the control group, the adverse reaction and efficacy was no significant variance（P 〉 0. 05 ）. Conclusion Treatment with valaciclovir hydrochloride tablets ＋ compound glycyrrhizin tablets is safe, effective, and good compliance for herpes zoster.
出处
《中国现代药物应用》
2010年第11期6-7,共2页
Chinese Journal of Modern Drug Application
关键词
带状疱疹
伐昔洛韦片
复方甘草酸苷片
疗效
后遗神经痛
Herpes zoster
Valaciclovir hydrochloride tablets
Compound glycyrrhizin tablets
Therapentic effect
Residual neuralgia
