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二甲双胍对2型糖尿病胰岛素抵抗及脂代谢紊乱的疗效观察 被引量:7

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摘要 目的:观察二甲双胍对2型糖尿病(T2DM)胰岛素抵抗(IR)及脂代谢紊乱的疗效。方法:将符合T2DM诊断并伴有超重及脂代谢紊乱的患者40例在强化生活方式干预的基础上予口服二甲双胍治疗4个月,比较治疗前后IR及脂代谢紊乱程度。结果:治疗后三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)降低,高密度脂蛋白胆固醇(HDL-C)上升(P均<0.01),外周INS敏感指数上升(P<0.05)。结论:二甲双胍联合强化生活方式干预对T2DM合并IR及血脂代谢紊乱的疗效显著。
作者 杨逸静
出处 《中国当代医药》 2010年第16期76-76,81,共2页 China Modern Medicine
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