摘要
目的探讨药物自我处置程式对精神分裂症患者康复的影响。方法将66例住院非急性期精神分裂症患者随机分为训练组(33例)和对照组(33例)。在抗精神病药物治疗不变的前提下,训练组按照《药物自我处置程式》进行分组训练8周,8周后两组随访6个月。采用社会功能缺陷量表(SDSS)和生活质量综合评定问卷(GQOLI-74)对两组患者进行评估。结果(1)训练8周末及随访6个月时,训练组的SDSS总分、GQOLI-74总分与对照组比较,差异有统计学意义(P<0.05)。SDSS总分:8周末时两组分别为(2.6±2.7)分与(4.9±3.1)分;6个月时两组分别为(1.7±2.4)分与(4.2±3.2)分。GQOLI-74总分:8周末时两组分别为(68.0±10.6)分与(61.1±12.2)分;6个月时两组分别为(70.3±9.9)分与(62.7±11.3)。(2)同组不同时点比较,①训练8周末及随访6个月时与入组时比较,训练组SDSS总分(2.6±2.7)分和(1.7±2.4)分与(6.8±3.1)分,P<0.05及两组GQOLI-74总分差异均有统计学意义(P<0.05);②随访6个月时与8周末比较,训练组的SDSS总分(1.7±2.3)分与(2.6±2.7)分,P=0.003及GQOLI-74总分(70.3±9.9)分与(68.0±10.6)分,P=0.041差异均有统计学意义;(3)相关分析显示,患者SDSS总分与GQOLI-74总分呈负相关(P=0.000)。结论《药物自我处置程式》训练能改善精神分裂症患者的社会功能,提高其生活质量,适宜广泛开展。
Objective To explore the effects of medication self-management module on social function and quality of life of patients with schizophrenia.Methods 66 inpatients with schizophrenia in their non-acute stage were randomly divided into training group（n=33） and control group（n=33）.Both groups received the anti-psychotics therapy.Medication self-management module was only given to the training group for 8 weeks.All subjects were follow up for 6 months and were evaluated with Social Disability Screening Schedule （SDSS） and Generic Quality of Life Inventory-74 （GQOIL-74）.Results （1） There were significant difference on the total scores of SDSS and the total scores of GQOIL-74 after 8W、6 months between training group and control group：The total scores of SDSS （2.6±2.7）vs（4.9±3.1）,（1.7±2.4）vs（4.2±3.2）,the total scores of GQOIL-74（68.0±10.6）vs（61.1±12.2）,（70.3±9.9）vs（62.7±11.3）.（2）Comparison of different points in time in the same group：①8 weeks and 6 months compared with the income,there were significant differences on the total scores of SDSS （2.6±2.7）and（1.7±2.4）vs（6.8±3.1）of training group and the total scores of GQOIL-74（P〈0.05） of two groups.②6 months compared with 8 weeks,there were significant differences on the total scores of SDSS （1.7±2.4）vs（2.6±2.7）,P=0.003 and the total scores of GQOIL-74 （70.3±9.9）vs（68.0±10.6）,P=0.041of training group.（3）Correlation analysis confirmed negative relation between the total scores of SDSS and the total scores of GQOIL-74 on 8 weeks and 6 months（P=0.000）.Conclusion Medication self-management module could significantly improve social function and quality of life of patients with schizophrenia.So it is suitable to popularize.
出处
《中国全科医学》
CAS
CSCD
北大核心
2010年第14期1514-1516,共3页
Chinese General Practice
基金
广西壮族自治区卫生厅项目(Z2007337)
关键词
药物自我处置程式
精神分裂症
社会功能
生活质量
Medication self-management module
Schizophrenia
Social function
Quality of life
