摘要
儿童性早熟是一种生长发育异常的疾病,表现为青春期特征提前出现,严重影响儿童的成年身高和心理健康。本文在回顾性早熟的定义、发病机制及分类有关理论的基础上,重点关注不同类型性早熟在发病机制、病因、诊断及鉴别诊断和辅助检查的研究现状及新进展。目前,对儿童性早熟较多采用子宫及卵巢超声检查,迄今对于这种性早熟类型的诊断及鉴别诊断价值尚存在争议。随着检测技术的发展,出现了如骨钙素、骨碱性磷酸酶等骨骼定量检测指标诊断儿童性早熟,但其诊断价值尚需进一步临床研究证实。
Precocious puberty is a disease in growth and development process which is characterized by the advanced appearance of secondary sex characteristics. Maturing earlier than one＇s peers has negative consequences in final height and psychosocial health. This paper reviews various definitions of precocious puberty and elucidates the theory of precocious puberty in pathogenesis and classification. The present situation of different types of precocious puberty in pathogenesis, diagnosis and differential diagnosis are elaborated. Etiology of various types of precocious puberty and progress in diagnose including auxiliary examination and laboratory test are well elaborated. Controversial results concerning ovaries and uterus ultrasound in diagnosis of precocious puberty still exist. With the development of laboratory tests, some assays such as osteocalcin and alkaline phosphatase are present. More clinical researches are needed to prove the diagnostic value.
出处
《中华妇幼临床医学杂志（电子版）》
CAS
2010年第3期223-225,共3页
Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition)
关键词
青春期
早熟
分类
诊断
病因学
puberty
precocious
classification
diagnose
etiology
