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PI3K-Akt抑制剂诱导人鼻咽癌细胞CNE2凋亡的作用 被引量:9

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出处 《临床耳鼻咽喉头颈外科杂志》 CAS CSCD 北大核心 2010年第8期370-372,共3页 Journal of Clinical Otorhinolaryngology Head And Neck Surgery
基金 广西自然科学基金(桂科自0728120)
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  • 2[3]Brognard J,Clark AS,Ni YC,et al.Akt/Protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation[J].Cancer Res,2001,61 (15):3986-3997.
  • 3[4]Liang J,Slingerland JM.Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression[J].Cell Cycle,2003,2(4):339-345.
  • 4[5]Takeda A,Osaki M,Adachi K,et al.Role of the phosphatidylinositol 3′-kinase-Akt signal pathway in the proliferation of human pancreatic ductal carcinoma cell lines[J].Pancreas,2004,28(3):353-358.
  • 5[6]Eugene SK,Jennifer S,Nathan M,et al.Activation of Akt/Protein Kinase B Overcomes a G2/M Cell Cycle Checkpoint Induced by DNA Damage[J].Mol Cell Biol,2002,22(22):7831-7841.
  • 6Choe G,Horvath S,Cloughesy TF,Crosby K,Seligson D,Palotie A,Inge L,Smith BL,Sawyers CL,Mischel PS.Analysis of the phosphatidylinosit ol 3'-kinase signaling pathway in glioblastoma patients in vivo[J].癌症,2003,22(7):766-766. 被引量:42

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