摘要
目的:探讨硫普罗宁注射液联合中药治疗非酒精性脂肪肝(NAFL)的实验性研究。方法:将50只NAFL大鼠随机分为两组,分别给予硫普罗宁注射液联合中药及单用硫普罗宁注射液治疗,3个月为1个疗程,观察治疗NAFL大鼠前后血清丙氨酸转氨酶(ALT)、γ-谷氨酰转肽酶(GGT)、甘油三酯(TG)、胆固醇(TCh)及肝脏组织形态学的变化。结果:治疗组总有效率为88%,而对照组52%(P<0.01)。结论:硫普罗宁注射液联合中药治疗NAFL疗效确切,值得临床推广。
Objective： To investigate the efficacy of tiopronin injection combined with traditional Chinese medicine （TCM） in the treatment of non--alcoholic fatty liver （NAFL）. Methods： Fifty SD rats with NAFL were randomly divided into two groups： treatment group , tiopronin injection plus TCM and control group, tio- pronin injection alone, with a 3-- month course of treatment in both groups. Serum ALT, GGT, TG, TCh and histomorphological changes in the liver were detected in both groups before and after treatment. Results： The total effective rate of the treatment group was 88% while that of the control group was only 52% （P 〈 0.01）. Conclusion： Tiopronin injection combined with TCM in the treatment of non--alcoholic fatty liver is proved to be effective and suitable in its clinical treatment.
出处
《黑龙江医药科学》
2010年第3期115-116,共2页
Heilongjiang Medicine and Pharmacy
关键词
硫普罗宁注射液
中西医结合疗法
非酒精性脂肪肝
tiopronin injection
traditional Chinese and western medicine therapy
non--alcoholic fatty liver
