摘要
目的探讨骨质疏松与青少年休门病(Scheuermann’s disease,SD)的关系。方法研究对象包括青少年SD患者10例和正常青少年30例。所有研究对象均行双能X线吸收仪测量非优势侧的股骨近端和腰椎(L2～4)的骨密度(bone mineral density,BMD),将2组受试者的测量结果进行t检验比较,并对SD组BMD结果与后凸Cobb角角度进行相关性分析。结果 2组受试者在年龄、性别比例、体重指数(body mass index,BMI)、腰椎及非优势侧股骨近端BMD上差异无统计学意义(P>0.05),SD组患者腰椎及非优势侧股骨近端BMD与后凸Cobb角角度无显著相关性(P>0.05)。结论骨质疏松可能不是青少年发生SD的致病因素,骨质疏松与SD的严重程度可能无关。
Objective To test the hypothesis that osteoporosis is an aetiological factor in the development of Scheuermann＇s disease in adolescents. Methods Ten individuals with Scheuermann＇s disease （SD） and 30 healthy adolescents were included in this study. Bone mineral density （BMD） at the lumbar spine （L2-4） and proximal femur of non-superiority side was measured by dual energy X-ray Absorptiometry in both groups and the results were compared by t-test. The correlation analysis was performed between BMD and Cobb＇s angle of kyphosis in Group SD. Results The age,sex ratio,body mass index （BMI） and BMD at lumbar vertebrae and proximal femur of non-superiority side in the patients with Scheuermann＇s disease were not significantly different from those in the controls （P0.05）. The BMD of the Scheuermann＇s disease patients had no significant correlations with the severity of the disease （P0.05）. Conclusion These results suggest that osteoporosis may be not an aetiological factor in Scheuermann＇s disease and it also does not correlate with the severity of the Scheuermann＇s disease.
出处
《脊柱外科杂志》
2010年第2期75-77,共3页
Journal of Spinal Surgery
基金
南京市卫生局重点项目(基金编号ZKX05016)
