摘要
目的探讨结直肠癌伴发肠系膜肿瘤结节与患者预后的关系。方法回顾性分析105例结直肠癌患者临床病理及随访资料,肠系膜肿瘤结节不作为T或N分期,生存率分析其与预后的关系。结果Dukes分'期:A期13例,B期42例,C期35例,D期15例。共计13(12.4%)例患者出现系膜内转移结节,其中Dukes'A期1例,B期4例,C期4例,D期4例。总5年生存率为71.4%,其中Dukes'A期为92.3%,B期为90.5%,C期为65.7%,D期为13.3%。伴有与不伴有肠系膜肿瘤结节的患者总5年生存率分别为38.5%及76.1%(P<0.05),在Dukes'A期为0%和100.0%(P<0.05),B期为50.0%和94.7%(P<0.05),C期为50.0%和67.7%(P>0.05),D期为25.0%和9.1%(P>0.05)。伴有肠系膜肿瘤结节的Dukes'A+B期患者5年生存率为50.0%,与Dukes'C期(65.7%,P>0.05)差异无统计学意义。结论结直肠癌伴有肠系膜肿瘤结节患者预后不良,其临床意义更类似于淋巴结转移。
Objective To investigate the clinical significance of mesenteric tumor nodules in patients with colorectal carcinoma.Methodes The clinic and patholgic data of 105 cases with colorectal malignant lesions were analyzed retrospectively.Dukes＇ staging was standardized by considering mesenteric tumor nodules（MTN） separately and not assigning them to T or N categories.Survival analyses were employed to find out the relationship between prognosis and MTN.Results According to Dukes＇ staging,13 cases were belonged to A stage,42 cases B stage,35 cases C stage and 15 cases D stage.There were 13 patients（12.4%） who presented MTN（Dukes＇ A stage 1 case,B stage 4cases,C stage 4 cases,D stage 4 cases）.The 5 years overall survival was 71.4%（（Dukes＇ A stage 92.3%,B stage 90.5%,C stage 65.7%,D stage 13.3%）.Between groups with and without MTN,the overall survival of 5 years was 38.5% vs.76.1%（P0.05）,Dukes＇ A stage was 0% vs.100.0%（P0.05）,B stage 50.0% vs.94.7%（P0.05）,C stage 50.0% vs.67.7%（P0.05）,D stage 25.0% vs.9.1%（P0.05）.Dukes＇ A and B stage cases with MTN had a similar 5 years overall survival with that of Dukes＇ C stage patients（50.0% vs.65.7%,P0.05）.Conclusions The cases with colorectal carcinoma combing with MTN presents a worse prognosis,and the significance of MTN may be similar to that of lymph node metastasis.
出处
《中华普外科手术学杂志（电子版）》
2010年第2期50-52,共3页
Chinese Journal of Operative Procedures of General Surgery(Electronic Edition)
关键词
结直肠肿瘤
肠系膜
淋巴转移
预后
Colorectal nelorectal Mesentery Lymphatic metastasis Prognosis
