摘要
目的:对清胰颗粒进行质量标准的研究。方法:采用薄层色普法对制剂中的大黄进行定性鉴别,用大黄素为对照品,以石油醚(30～60℃)-甲酸乙酯-甲酸(15:5:1)的上层液为展开剂。采用高效液相色谱法对栀子中栀子苷进行含量测定,采用迪马钻石色谱柱(200mm×0.46mm)。流动相为:乙晴-水(15:85),检测波长为238nm,流速1.0mL/min。结果:3批清胰颗粒中含栀子苷(C17H24O10)1.3606～1.4927。平均加样回收率为98.88%,RSD为1.63%。结论:该法可作为该产品的质量控制方法。
Objective：Studies on quality for Qingyi granules.Methods ：Rhubarb in the herbal medicines was identified by TLC.Light petroleum（30～60℃）-ethyl formate-formic acid（15 ：5 ：1）was used as developing solvent for Rhubarb with emodin as reference standard.the contents of jasminoidin in cape jasmine was determined by HPLC.The chromatographic conditions were as follow ：DIMA diamond Column（0.46mm×200mm）.The mobile phase consisted of acetonitrile-water（15 ：85）.The detection wavelength was 230nm,flow rate was 1.0mL/min.Results ：The contents of jasminoidin in 3 batches of the qingyi granules were 1.3606～1.4927.The average recovery was 98.88%,RSD was 1.63%.Conclusion ：The method can be used for the quality control of qingyi granues.
出处
《辽宁中医药大学学报》
CAS
2010年第6期45-46,共2页
Journal of Liaoning University of Traditional Chinese Medicine
基金
贵州省中医药管理局中医药资助项目(D-227)
