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46例无创正压治疗COPD急性加重期伴呼吸衰竭临床分析 被引量:1

Noninvasive positive pressure ventilation for respiratory failure secondary to acute exacerbations of COPD: a clinical analysis of 46 cases
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摘要 目的 探讨无创正压治疗COPD急性加重期伴呼衰的临床疗效.方法 选择2007年1月-2009年12月收治于我院的COPD急性加重期伴呼衰患者92例.随机分为治疗组46例和对照组46例.对照组采用常规疗法治疗 治疗组在常规治疗的基础上加用无刨正压通气治疗,比较两组治疗效果.结果 经过治疗,治疗组PaCO2(89.26±9.27)mm Hg,PaO2(89.26±9.27)mm Hg,呼吸频率(21.2±1.3)次/分,治疗效果显著优于对照组(P〈0.05).结论 无创正压通气治疗COPD急性加重期伴呼衰患者,能有效的降低PacO2、呼吸频率和提高PaO2等,具有较好的临床疗效. Objective To evaluate the efficacy of noninvasive positive pressure ventilation for respiratory failure secondary to acute exacerbations of COPD. Methods From January 2007 to December 2009, 92 patients were randomly assigned to receive conventional therapy alone (control group, 46 patients) or the same therapy plus noninvasive positive pressure ventilation (study group, 46 patients). The efficacy was compared between the two groups. Results After treatment, observe groups have better therapeutic efficacy than control groups in degrading PaCO2, degrading respiratory frequency, and elevating PaO2. Conclusions Noninvasive positive pressure ventilation for respiratory failure secondary to exacerbations of COPD can effectively decrease PaCO2 level and respiratory rate and increase PaO2 level. It has a better efficacy.
作者 许进雄
机构地区 汕尾市人民医院
出处 《国际医药卫生导报》 2010年第11期1342-1344,共3页 International Medicine and Health Guidance News
关键词 无创正压通气 COPD 急性加重期 呼吸衰竭 Noninvasive positive pressure ventilation Chronic obstructive pulmonary disease Acute exacerbation Respiratory failur
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