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生物学软件在线粒体DNA序列多态性分析中的应用 被引量：4

Application of biological softwares for mtDNA sequence polymorphism analysis
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摘要 对线粒体DNA(mtDNA)序列进行多态性分析,将有利于从母系遗传的角度研究各人群的源流、迁移以及亲缘关系等情况。探讨利用Internet共享生物学软件对各种生物样本mtDNA高变区进行序列比对分析及多态性分析,结果显示DNAstar、ClustalX、DnaSP以及Mega等软件操作简便、易于判读、结果准确可靠,可广泛应用于人类学、系统发育学以及法医鉴定等领域的研究。 The sequence polymorphism analysis of mitochondrial DNA（mtDNA） is helpful to explore the origins , migrations and relationships of polulations. The free biological softwares including DNAstar, ClustalX, DnaSP, Mega and so zn were applied to perform mtDNA sequence comparison and polymorphism analysis. The results showed that these softwares are manipulable, easy - to - interpret , reliable and can be used as tools for the study of anthropolgy, phylogenetics and forensicmedicine.
作者 李彬彬 黄培春 钟复光
机构地区 广东医学院病理生理学教研室 贵阳医学院医学科学研究所
出处 《生物信息学》 2010年第2期153-155,共3页 Chinese Journal of Bioinformatics
基金 国家自然科学基金资助项目(39560035) 湛江市科技计划项目(2007C04005)
关键词 生物学软件 线粒体DNA 多态性 Biological software MtDNA Polymorphism
分类号 Q51 [生物学—生物化学]
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参考文献8

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二级参考文献23

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生物信息学
2010年 第2期

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