摘要
目的:考察盐酸左氧氟沙星注射液与肌苷氯化钠注射液配伍稳定性。方法:在室温(20℃)条件下,采用紫外分光光度法考察不同浓度的盐酸左氧氟沙星注射液与肌苷氯化钠注射液配伍后2药在6h内含量变化,并考察配伍液的外观、pH值及不溶性微粒变化情况。结果:盐酸左氧氟沙星注射液与肌苷氯化钠注射液配伍后外观、pH值、含量、不溶性微粒均无明显变化。结论:临床上可将盐酸左氧氟沙星注射液与肌苷氯化钠注射液直接配伍后6h内使用。
OBJECTIVE：To study the compatible stability of Levofloxacin hydrochloride injection with Inosine in sodium chloride injection. METHODS：Levofloxacin hydrochloride injection was mixed with Inosine in sodium chloride. Then UV spectrophotometry was applied to detect the change of content at 20 ℃ within 6 hours. The change of appearance,pH value,content of mixture,insoluble particle were also observed. RESULTS：The change of appearance,pH value,content of mixture,insoluble particle in mixture was not found out. CONCLUSION：Levofloxacin hydrochloride injection mixing with Inosine in sodium chloride injection is suitable for clinical use within 6 h.
出处
《中国药房》
CAS
CSCD
北大核心
2010年第22期2073-2075,共3页
China Pharmacy
关键词
盐酸左氧氟沙星注射液
肌苷氯化钠注射液
配伍
稳定性
Levofloxacin hydrochloride injection
Inosine in sodium chloride injection
Compatible
Stability
