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开展以遗传学类型分类骨髓增生异常综合征的针对性治疗研究 被引量：11

Treatment focused on myelodysplastic syndromes based on cytogenetic categories
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摘要 骨髓增生异常综合征（MDS）是一组起源于造血干（祖）细胞的克隆性异质性疾患,其异质性不仅表现在外周血和骨髓象上,也表现在细胞遗传学、病程、转归和对治疗的反应上.MDS遗传学分型应是一种能反映疾病本质的分型方法 .国内应开展MDS遗传学分型的生物学特征研究,以MDS遗传学分型指导MDS的临床分型治疗,提高其临床疗效. Myelodysplastic syndromes （MDS） are heterogeneous clonal stem cell disorders characterised not only by peripheral cytopenia and bone marrow hyperplasia but also by karyotype. The course of disease, clinical outcome and response to treatment. Cytogenetic categories is a pattern typing the intrinsical features of MDS. It is suggested here that investigating biological characters and group treatment in MDS based on cytogenetic categories may enhance the therapeutic effect and bring benefit to MDS patients.
作者 麻柔 胡晓梅
机构地区 中国中医科学院西苑医院血液科
出处 《白血病．淋巴瘤》 CAS 2010年第5期262-264,共3页 Journal of Leukemia & Lymphoma
关键词 骨髓增生异常综合征 遗传学分型 分型治疗 Myelodysplastic syndromes Cytogenetic categories Group treatment
分类号 R551.3 [医药卫生—血液循环系统疾病]
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参考文献19

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二级参考文献70

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引证文献11

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白血病．淋巴瘤
2010年 第5期

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