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人脑弥散加权平面回波磁共振成像 被引量:26

Magnetic Resonance Diffusion weighted Echo planar Imaging of Human Brain
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摘要 目的:探讨正常人脑及脑梗塞弥散加权平面回波成像(DWEPI)的特点。材料与方法:28例健康志愿者及15例脑梗塞患者均作DWEPI,分析其表现并计算正常人脑组织、脑梗塞区的表面弥散系数(ADC)及相对ADC(rADC)。结果:正常人脑脊液、灰质、顶、额、枕叶白质的ADC平均值分别为3.12、0.89、0.71、0.80、0.84×10-3mm2/s;急性期脑梗塞在DWI上表现为高信号,ADC值下降为0.57~0.62×10-3mm2/s,DWI对病变的显示明显优于常规T2WI;亚急性期和慢性期脑梗塞表现为高或等信号,平均ADC值分别为0.71、1.27×10-3mm2/s,DWI所示的高信号范围与常规T2WI不完全一致。结论:DWEPT对脑梗塞的早期诊断及评价起重要的作用。 Objective: To evaluate the diffusion weighted echo planar imaging (DW EPI) features of brain in normal subjects and in patients with cerebral infarction.Materials and Methods:DW EPI was performed in 28 healthy volunteers and 15 patients with cerebral infarction. Apparent diffusion coefficient (ADC) and relative ADC of normal tissues and cerebral infarcts were calculated.Results:In normal subjects, the ADC values of cerebrospinal fluid, gray matter, and parietal, frontal, occipital white matter were 3.12, 0.89, 0.71, 0.80, and 0.84×10 -3 mm 2/s, respectively. Acute infarcts appeared as areas of hyperintensity on DW images, with a decreased ADC of 0.57~0.62×10 -3 mm 2/s. The lesions were more readily shown on DWI than on conventional T 2WI. Subacute and chronic infarcts presented hyperintensity or isointensity on DW images, with an average ADC of 0.71 and 1.27×10 -3 mm 2/s respectively. The areas of hyperintensity on DW images were not fully consistent with that on conventional T 2WI.Conclusion: DW EPI plays an important role in making early diagnosis and evaluation of cerebral infarction.
出处 《临床放射学杂志》 CSCD 北大核心 1999年第3期133-136,共4页 Journal of Clinical Radiology
关键词 脑梗塞 磁共振成像 弥散 DW-EPI Brain Cerebral infarction MRI Diffusion
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